Main description:

This book provides an overview of the history of integrative bioinformatics and the actual situation and the relevant tools. Subjects cover the essential topics, basic introductions, and latest developments; biological data integration and manipulation; modeling and simulation of networks; as well as a number of applications of integrative bioinformatics. It aims to provide basic introduction of biological information systems and guidance for the computational analysis of systems biology. This book covers a range of issues and methods that unveil a multitude of omics data integration and relevance that integrative bioinformatics has today. It contains a unique compilation of invited and selected articles from the Journal of Integrative Bioinformatics (JIB) and annual meetings of the International Symposium on Integrative Bioinformatics.

Contents:

Chapter 1. Integrative Bioinformatics: History and Perspective.- Chapter 2. From Genotypes to Phenotypes - A Plant Perspective on Current Developments in Data Management and Data Publication.- Chapter 3. Research data resources for epidemiology.- Chapter 4. Data Warehousing of Life Science Data.- Chapter 5. Automation in Graph-Based Data Integration and Mapping.- Chapter 6. DaTo: an Integrative Web Portal for Biological Databases and Tools.- Chapter 7. The Use of Data Integration and Knowledge Graphs in Modern Molecular Plant Breeding.- Chapter 8. Integrative data analysis and exploratory data mining in biological knowledge graphs.- Chapter 9. Exploring plant transcription factor regulatory networks.- Chapter 10. Microbiome and big-data mining.- Chapter 11. Data Integration Applications in Medical Information Systems.- Chapter 12. Visualising Metabolic Pathways and Networks: Past,Present,Future.- Chapter 13. Comprehensive open-source Petri net toolchain for modeling and simulation in systems biology.- Chapter 14. Immersive Exploration of Cell Localization Scenarios using VR, Spatialized Video Communication and Integrative Bioinformatics.- Chapter 15. IoS: a Needed Platform for Scientific Workflow Management.- Chapter 16. Revealing genotype-phenotype interactions: The AgroLD experience and challenges.- Chapter 17. Interactive Data Analyses Using Tbtools.- Chapter 18. Analyzing multi-omic data with integrative platforms.