Main description:

This book takes an in depth and hard look at the current status and future direction of treatment predictive markers in Personalized Medicine for the brain from the perspectives of the researchers on the cutting edge and those involved in healthcare implementation. The contents provide a comprehensive text suitable as both a pithy introduction to and a clear summary of the "science to solutions" continuum in this developing field of Personalized Medicine and
Integrative Neuroscience. The science includes both measures of genes using whole genome approaches and SNIPS as well as BRAINmarkers of direct brain function such as brain imaging, biophysical changes and objective cognitive and behavioral measurements. Personalized Medicine for Brain Disorders will soon
be a reality using the comprehensive quantitative and standardized approaches to genomics, BRAINmarkers and cognitive function. Each chapter provides a review of recent relevant literature; show the solutions achieved through integrative neuroscience and applications in patient care thus providing a practical guide to the reader. The timeliness of this book's content is propitious providing bottom line information to educate practicing clinicians, health care workers and researchers, and also a
pathway for undergraduate and graduates interested in further their understanding of and involvement in tailored personal solutions.

Contents:

PREFACE, Herbert Pardes, MD
INTRODUCTION, Stephen H. Koslow, PhD and Evian Gordon, MD, PhD

GENESIS OF PERSONALIZED MEDICINE
1. The History of Personalized Medicine, Edward Abrahams, Ph.D. and Michael Silver
2. An Applied Context for Personalized Medicine in Psychiatry, Alan F. Schatzberg, MD
3. Personalized Medicine and Integrative Neuroscience: Towards Consensus Markers for Disorders of Brain Health, Leanne Williams, PhD and Evian Gordon MD, PhD

PERSONALIZED MEDICINE AND MENTAL DISORDERS
4. Does fMRI have a role in personalized health care for psychiatric patients?, Alex Fornito, MD and Edward T. Bullmore, MD
5. Stress and the Impact of Personalized Medicine, Charles F. Gillespie, M.D., PhD, Elisabeth B. Binder, MD, PhD, Paul E. Holtzheimer, MD, and Charles B. Nemeroff, MD, PhD
6. Personalized Medicine for Schizophrenia, Jacob S. Ballon, MD, Ragy R. Girgis, MD, and Jeffrey A. Lieberman, MD
7. Personalized Integrative Markers for Attention Deficit/Hyperactivity Disorder in Children and Adolescents, M. Kohn, MD, S. Clarke, MD and Leanne Williams, PhD

PERSONALIZED MEDICINE AND OTHER BRAIN DISORDERS
8. The Role of Neuroimaging Biomarkers in Personalised Medicine for Neuro-degenerative and Psychiatric Disorders, Ellen M. Migo, Steve C. R. Williams, William R. Crum, Matthew J. Kempton and Ulrich Ettinger
9. Autonomic Nervous System Markers for Psychophysiological, Anxiety and Physical Disorders, Richard Gevirtz, Ph.D., BCIAC
10. Personalized Medicine in Sleep Health, Ronald Grunstein, MD
11. Theranostics and Translation towards Personalized Medicine for Multiple Sclerosis, Ariel Miller, Tamar Paperna, Opher Caspi, Izabella Lejbkowicz, Elsebeth Staun-Ram, Nili Avidan

PERSONALIZED MEDICINE AND HEALTH CARE
12. Brain-Related Healthcare: New Models for Personalized Medicine, David Whitehouse, MD
13. Clinical Decision Support in Employee Assistance Programs: Personalizing the Therapeutic Approach, Eugene Baker, PhD
14. Economic impacts of the Personalized Medicine Tsunami, Dan Segal and David Williams

CONCLUSION AND RECOMMENDATIONS
Accelerating the Future of Personalized Medicine, Evian Gordon, MD, PhD and Stephen H. Koslow, PhD