Main description:

This book represents the most current, comprehensive, and authoritative study of integrins on the market today. It provides an overview of the diverse biological functions of integrins, including:

The structure and functions of integrin cytoplasmic domains, the role of b2 integrins in leukocyte adhesion, the role of platelet membrane fibrinogen receptor glycoprotein IIb-IIIa (aIIbb3) in thrombosis and hemostasis, the functions of aV integrin family, the role of integrins in signal transduction, the role of integrins in carcinoma cells, the role of integrins in internalization of microbial pathogens through the binding of Yersinia pseudotuberculosis invasin protein, the role of integrins in the skin, the integrin function in early vertebrate development using amphibian embryos.

Key selling features:

the structure and functions of integrin cytoplasmic domains

the role of b2 integrins in leukocyte adhesion

the role of platelet membrane fibrinogen receptor glycoprotein IIb-IIIa (aIIbb3) in thrombosis and hemostasis

the functions of aV integrin family

the role of integrins in signal transduction

Contents:

Structure, Biochemical Properties, and Biological Functions of Integrin Cytoplasmic Domains. The Role of b2 Integrins in Leukocyte Adhesion. Platelet Membrane Glycoprotein IIb-IIIa (aIIbb3). The aV Integrins. Signaling To and From T Cell Integrins. Integrins as Signal Transduction Receptors. Integrin Receptors and Epiligrin in Cell-Cell and Cell-Substrate Adhesion in the Epidermis. Expressions of the Integrin a6b4 in Epithelial and Carcinoma Cells. Internalization of Microbial Pathogens by Integrin Receptors and the Binding of Yersinia pseudotuberculosis Invasin Protein. Integrin Function in Early Vertebrate Development. Perspectives from Studies of Amphibian Embryos