Main description:

This volume is a continuation of Volume 1 following the previously published Editorial. More emphasis is given to novel nanocarrier designs, their characterization and function, and applications for drug discovery and treatment. A number of chapters will deal with nanofibers as a new major application within the biomedical field with a very high success rate particularly in wound healing and diabetic foot and spine injuries. A major new subdivision will deal with mathematical methods for the assembly of nanocarriers both for simulation and function.

Contents:

Editorial and Introduction to Volume 2
Ales Prokop, Yasuhiko Iwasaki and Atsushi Harada

Part I Novel nanocarrier design and processing

Proprietary nanofiber technologies and scale-up
Stanislav Petrik

Magnetically responsive (nano)biocomposites
Ivo Safarik, Katerina Horska, Kristyna Pospiskova, Zdenka Maderova and Mirka Safarikova

Zwitterionic nanocarriers for gene delivery
Yu-Ju Shih, Ching-Wei Tsai, Lemmuel L Tayo and Yung Chang

Stimuli-responsive polymeric nanocarriers as promising drug and gene delivery systems
Gurusamy Saravanakumar and Won Jong Kim

Photo-responsive polymeric nanocarriers for on-demand drug delivery
Jian Ji and Qiao Jin

Part II Nanocarrier characterization and function

Considerations on uptake and intracellular trafficking of nanocarriers
Seyed Moien Moghimi, Helene Andersen and Ladan Parhamitar

Mucus as physiological barrier to intracellular delivery
Eleonore Froehlich and Eva Roblegg

Investigation of nanoparticles in biological objects by electron microscopy techniques
Gabriela Kratosova, Katerina Dedkova, Ivo Vavra and Fedor Ciampor

Gold nanoparticles for high resolution imaging in modern immunocytochemistry
Adam Schroefel, Dusan Cmarko, Eva Bartova and Ivan Raska

Design of functional polymers for intracellular drug nucleic acids delivery
Nobuhiro Nishiyama, Hiroyasu Takemoto

Membrane-domain-selective drug targeting based on lipid modification
Takeshi Mori and Yoshiki Katayama

Multifuntional protein-based nanoparticles for theragnosis
Vannucci Luca, Elisabetta Falvo and Pierpaolo Ceci

Cytocompatible phospholipid polymer for noninvasive nanodevice
Tomohiro Konno

Intracellular protein delivery using self-assembled amphiphilic polysaccharide nanogels
Asako Shimoda, Shin-ichi Sawada and Kazunari Akiyoshi

Part III Simulation for delivery and function

Molecular dynamics simulations of polyplexes and lipoplexes
Deniz Meneksedag-Erol, Chongbo Sun, Tian Tang, and Hasan Uludag

Computational studies of highly pegylated sterically stabilized micelles self-assembly and drug solubilization
Lela Vukovic and Petr Kral

Toward intracellular delivery and drug discovery
Stochastic logic networks as efficient computational models for gene regulatory networks
Peican Zhu, Jinghang Liang and Jie Han

Part IV Nanocarriers for drug discovery and treatment

Nanodiamonds as intracellular probes for imaging in biology and medicine
Jitka Slegerova, Ivan Rehor, Jan Havlik, Helena Raabova, Eva Muchova and Petr Cigler

Intracellular delivery of RNA using RNA-binding proteins or peptides
Kazunori Watanabe and Takashi Ohtsuki

Hyaluronic acid based nanofibers for wound dressing and drug delivery carriers
Jana Ruzickova., Vladimiir Velebny, Jindrich Novak J., Katarzyna Szuszkiewicz, Katerina Knotkova, Marcela Foglarova and Marek Pokorny Potential of siRNA therapy in chronic myeloid leukemia
Juliana Valencia-Serna, Breanne Landry, Xiaoyan Jiang and Hasan Uludag