Main description:

This volume covers the emerging area of science, Clinical Lipidomics, which is the application of lipidology to the understanding of physiological and pathophysiological changes of lipidomes, with a special focus on lipidomic profiles in human diseases.

Lipidomics is widely used to map lipid molecular species in a biological system. Clinical lipidomic analysis has demonstrated the comprehensive characterization of molecular lipids in various severities, durations, and therapies as a critical tool in identification and validation of disease-specific biomarkers.

This volume on Clinical Lipidomics will add to the literature and help advance the knowledge of the pathogenesis, diagnosis, prevention and treatment of diseases.

Contents:

Significance of Clinical Lipidomics
Xiangdong Wang MD, PhD, Distinguished Professor of Medicine, Director of Shanghai Institute of Clinical Bioinformatics, Executive Director of Clinical Science Institute of Fudan University Zhongshan Hospital, Deputy Director of Shanghai Respiratory Research Institute, Shanghai, China

Membrane lipidomics and personalised health
Carla Ferreri, ISOF, Consiglio Nazionale delle Ricerche, Bologna, Italy

Mitochondrial Lipid Metabolism and Diseases
Linlin Zhang, Clinical Science Institute of Fudan University Zhongshan Hospital, Shanghai, China;
Aurelio Reyes, MRC Mitochondrial Biology Unit (MRC MBU), University of Cambridge, UK

Breast cancer and lipid metabolism: Apoptosis and Cancer Therapy
Chunfa, Huang, Division of Hematology/Oncology, Department of Internal Medicine, School of Medicine and Cancer Center, Saint Louis University, USA;

Lipidomics in gastric cancer
Hui Zhang, Henan Province People Hospital, Zhangzhou, China

Changes of circulating lipidomes in lung cancer
Jiapei Lv, Clinical Science Institute of Fudan University Zhongshan Hospital, Shanghai, China;
Madhav Bhatia, Department of Pathology, University of Otago, Christchurch, New Zealand.

Lipidomics in Liver Cancer
Huoli Shen, PhD, Associate Professor of Metabolomics, Fudan University Institute of Biomedicine, Shanghai, China;

Lipidomics in Neurodegenerative Diseases
Dongming Cai, Department of Neurology, Alzheimer Disease Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA;

Clinical lipidomics in cystic fibrosis
Mario Ollero, Institut Mondor de Recherche Biomedicale, INSERM, Hopital Henri Mondor, France;

Clinical sphingolipidomics
Alfred Merrill, Schools of Chemistry and Biochemistry, Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, USA;

Differential Sphingolipid and Phospholipid Profiles in liver diseases
Suzanne de la Monte, Liver Research Center, Division of Gastroenterology and Department of Medicine, Brown University, Providence, RI, USA

Dendritic Cell Metabolism and Lipidomices
Duojiao Wu, MD, PhD, Associate Professor of Medicine, Office Director of Clinical Science Institute of Fudan University Zhongshan Hospital, Assistant Director of Shanghai Institute of Clinical Bioinformatics, Shanghai, China;

The emerging roles of extracellular vesicle - shuttling molecules as biomarkers
Yang Jin, Division of Pulmonary and Critical Care Medicine, Department of Medicine, Boston University, USA

Lipidomics in alcohol use disorder
Seth Devanshi, Discipline of Clinical Medicine & Addiction Medicine, Faculty of Medicine, University of Sydney, Australia;

Lipid-mediated Protein-protein Interactions Modulate Respiration-driven ATP Synthesis
Peter Brzezinski, Department of Biochemistry and Biophysics, Arrhenius Laboratories for Natural Sciences, Stockholm University, Sweden