Main description:

This issue of Neurosurgery Clinics, guest edited by Drs. Guy McKhann and Hugues Duffau, with consulting editors Russell R. Lonser and Daniel K. Resnick, will focus on Low-Grade Glioma. Topics includes, but are not limited to, Epidemiology and Molecular Epidemiology; WHO Pathological and Molecular Classification; Molecular Pathogenesis; Glioma Cell Migration and Heterogeneity; Clinical Presentation, Natural History, and Prognosis; LGG Epilepsy; MRI, fMRI, DTI, Molecular Imaging; Brain Mapping Techniques in LGG; Surgical Adjuncts to Increase EOR iMRI, Flourescence, Raman Histology; Mapping Cognition and Emotion; Extent of Resection; EOR vs Molecular Classification; Chemotherapy Treatment and Trials; Radiotherapy Treatment and Trials; Higher Order Surgical Questions; and Building a Glioma Practice.

Contents:

1. Epidemiology and Molecular Epidemiology
2. Molecular Pathogenesis
3. Alterations in the Brain Microenvironment in Diffusely Infiltrating Low Grade Glioma
4. Clinical Presentation, Natural History and Prognosis of Diffuse Low-Grade Gliomas
5. LGG Epilepsy
6. Mapping in Low Grade Glioma Surgery: Low and High Frequency Stimulation
7. Surgical Adjuncts to Increase EOR iMRI, Fluorescence, Raman Histology
8. Beyond Language: Mapping Cognition and Emotion
9. Evidence for Improving Outcome through Extent of Resection
10. EOR Versus Molecular Classification: What Matters When?
11. Chemotherapy Treatment and Trials in Low Grade Gliomas
12. Low-Grade Glioma Radiotherapy Treatment and Trials
13. Higher Order Surgical Questions for Diffuse Low-Grade Gliomas: Supramaximal Resection, Neuroplasticity and Screening
14. Building a Glioma Practice