Main description:

This book provides the reader with a multidisciplinary approach that is state of the art and reflects input from the European Neuroendocrine Tumor Society and the North American Neuroendocrine Tumor Society. In particular, the text focuses on the pathophysiology of neuroendocrine tumors and includes a comprehensive review of the most recent developments in understanding the complex hormone and receptor signaling that is important for the future development of potent pharmacological treatments. The volume reviews the pathological grading and staging systems providing useful clinical information for the treating clinician as well as a useful reference for pathologists. The clinical management of neuroendocrine tumors is reviewed enabling the treating physician to understand the diagnostic approaches to differentiating the various types of neuroendocrine tumors. In addition, the treatments are reviewed in great detail and include novel radiological, surgical, and chemotherapeutic approaches.

The reader will utilize this book as both a comprehensive and quick reference guide through the use of diagnostic and treatment algorithms. Written by international experts in their particular field of study, Management of Pancreatic Neuroendocrine Tumors will be of great value to medical oncologists, endocrinologists, gastroenterologists, pathologists, surgeons, and diagnostic and interventional radiologists.

Contents:

1 Pathology of Pancreatic Neuroendocrine Tumors

Nils Lambrecht

2 Inherited and Somatic Genetics of Pancreatic Neuroendocrine Tumors

Lauren Fishbein, Katherine L. Nathanson

3 Laboratory Assessment of NETS

Christos Toumpanakis

4 Zollinger-Ellison Syndrome: Diagnosis and Management

Maneesh H. Singh, David C. Metz

5 Clinical Manifestations of Multiple Endocrine Neoplasia, Type 1

Susan Yuditskaya, Monica C. Skarulis

6 Gastric Carcinoids: Classification and Diagnosis

Kali Zhou, Wendy Ho

7 Endoscopic Approaches for Diagnosis of Pancreatic Neuroendocrine Tumors

Tarun Rustagi, James J. Farrell

8 Endoscopic Approaches to Treatment of Pancreatic Neuroendocrine Neoplasms

Amit Raina, Vinay Chandrasekhara

9 Surgical Approaches to Neuroendocrine Tumors

James Wu, F. Charles Brunicardi

10 Radiotherapy and Radiopharmaceuticals for the Treatment of Pancreatic Neuroendocrine Tumors

Lowell Anthony

11 Nuclear Medicine Approaches to Treatment of Neuroendocrine Tumours

Ken Herrmann, Rudolf A. Werner, Christina Blumel, Martin S. Allen-Auerbach

12 Novel Targets for Future Medical Treatments

Sandy T. Liu, Andrew E. Hendifar, Edward M. Wolin