Main description:

Cytogenetics is the study of the structure and function of the cell, particularly chromosomes.

Manual of Cytogenetics in Reproductive Biology examines the diagnostic role of cytogenetics in improving the outcome of assisted reproductive technologies (ART).

Divided into six sections, the book begins with the basics of genetics, followed by investigative cytogenetics, applied cytogenetics, recent advances, preimplantation and prenatal cytogenetics.

This comprehensive guide includes nearly 200 clinical images, diagrams and tables, and is an invaluable reference for practising specialists in genetics, infertility and obstetrics and gynaecology.

Key points

Examines diagnostic role of cytogenetics in improving outcome of ART
Six sections each providing in depth coverage of different aspects of cytogenetics
Includes nearly 200 clinical images, diagrams and tables
Invaluable for specialists in genetics, infertility and OBSGY

Contents:

Section 1: Basics of Genetics and Genetics Laboratory

Structure of DNA
Chromosome Nomenclature and Cell Division
Microscopes in Assisted Reproductive Technology
The Cell Cycle and Cell Division
Cell

Section 2: Investigative Cytogenetics

Cytogenetics
Polymerase Chain Reaction
Human Chromatin
Molecular Techniques in Preimplantation Genetic Diagnosis

Section 3: Applied Cytogenetics

DNA Fragmentation and Pregnancy Loss
Cytogenetics of Infertile Women
Cloning
Premature Ovarian Failure: A Chronic Debilitating Condition of Womanhood
Genetics and Male Infertility
Sperm DNA Damage Assessment: Techniques and Relevance in Male Infertility Diagnostics
Patterns of Inheritance
Epigenetics
Inborn Errors of Metabolism
Male Infertility and Cytogenetics
Cytogenetics in Recurrent Miscarriages
Chromosomal Polymorphic Variants and Reproductive Outcome
Oocyte and Maternal Inheritance

Section 4: Cytogenetics: Recent Advances

Cell Sorting in Genomics: Beginners' Guide
Gene Therapy
Recombinant DNA Technology
Blot Tests
Whole Genome Amplification and CGH: Recent Molecular Biology Techniques in Cytogenetics
Soluble Human Leukocyte Antigen-G: Embryology in the Era of Proteomics
Role of Centrosome in Fertilization and Beyond in Assisted Reproduction
Human Genome Project

Section 5: Preimplantation Cytogenetics

Preimplantation Genetic Diagnosis: A Review
Preimplantation Genetic Diagnosis in Assisted Reproductive Technology

Section 6: Prenatal Cytogenetics: Clinical Applications

Prenatal Cytogenetics
Prenatal Diagnosis of Down Syndrome and other Chromosomal Disorders and Counseling for Abnormal Serum Marker Analytes
Common Genetic Syndromes in Clinical Practice
Assisted Reproductive Technology and Genetic Counselling