Main description:

This issue of Immunology and Allergy Clinics, guest edited by Mariana C. Castells, MD, is devoted to Mastocytosis. Articles in this issue include: New Insight into Clonal Mast Cell Disorders Including Mastocytosis; Cutaneous Mastocytosis in Adults and Children: New Classification and Prognostic Factors; Hymenoptera Anaphylaxis as a Clonal Mast Cell Disorder; Non Clonal Mast Cell Activation Syndrome: A growing body of evidence; Familial Tryptasemia Syndromes: Genotyping and Symptoms; POTS and EDS: Entities Associated to Mast Cell Activation; KIT Mutations: New Insight and Diagnostic Value; Patients' Perceptions in Mast Cell Activation Disorders; Mast Cell Mediators of Significance in Clinical Practice; Tyrosine Kinase Inhibition in Mast Cell Activation Disorders; Gastrointestinal Involvement in Mast Cell Activation Disorders; Bone Marrow Expression of Mast Cell Disorders; Genomics and Proteonomics in Clonal Mast Cell Disorders; and Pediatric Expression of Mast Cell Activation Disorders.

Contents:

Foreword: The Many Faces of Mast Cell Disorders

Preface: Mastocytosis: Moving the Field to Precision and Personalized Medicine

New Insights into Clonal Mast Cell Disorders Including Mastocytosis

Cutaneous Mastocytosis in Adults and Children: New Classification and Prognostic Factors

Pediatric Expression of Mast Cell Activation Disorders

Bone Marrow Expression of Mast Cell Disorders

Mast Cell Mediators of Significance in Clinical Practice in Mastocytosis

Kit Mutations: New Insights and Diagnostic Value

Gastrointestinal Involvement in Mast Cell Activation Disorders

Bone Disease in Mastocytosis

Hymenoptera Anaphylaxis as a Clonal Mast Cell Disorder

Nonclonal Mast Cell Activation Syndrome: A Growing Body of Evidence

Hereditary Alpha Tryptasemia: Genotyping and Associated Clinical Features

Association of Postural Tachycardia Syndrome and Ehlers-Danlos Syndrome with Mast Cell Activation Disorders

Patient Perceptions in Mast Cell Disorders

Tyrosine Kinase Inhibition in Mastocytosis: KIT and Beyond KIT