Main description:

Matrix Metalloproteinases and Tissue Remodeling in Health and Disease: Target Tissues and Therapy, Volume, Volume 148, the latest volume in the Progress in Molecular Biology and Translational Science series covers a variety of timely topics, with chapters focusing on The Role of Matrix Metalloproteinases in Development, Repair, and Destruction of the Lungs, Matrix Metalloproteinases in Kidney Disease: Role in Pathogenesis and Potential as a Therapeutic Target, Regulation of Matrix Metalloproteinase in the Pathogenesis of Diabetic Retinopathy, Matrix Metalloproteinases in Normal Pregnancy and Preeclampsia, and Matrix Metalloproteinases, Neural Extracellular Matrix, and Central Nervous System Pathology.

This volume is the second part of a thematic on matrix metalloproteinases and tissue remodeling in health and disease. It focuses on the role of MMPs in other systems, target tissues, and pathological disorders and the potential benefits of MMP inhibitors in various disorders.

Contents:

1. The Role of Matrix Metalloproteinases in Development, Repair, and Destruction of the Lungs Amanda Y. Hendrix and Farrah Kheradmand 2. Matrix Metalloproteinases in Kidney Disease: Role in Pathogenesis and Potential as a Therapeutic Target Alan R. Parrish 3. Regulation of Matrix Metalloproteinase in the Pathogenesis of Diabetic Retinopathy Renu A. Kowluru and Manish Mishra 4. Matrix Metalloproteinases in Normal Pregnancy and Preeclampsia Juanjuan Chen and Raouf A. Khalil 5. Matrix Metalloproteinases, Neural Extracellular Matrix, and Central Nervous System Pathology Ciro De Luca and Michele Papa 6. Matrix Metalloproteinases in Bone Resorption, Remodeling, and Repair Katiucia B.S. Paiva and Jose M. Granjeiro 7. Matrix Metalloproteinases and Synovial Joint Pathology Charles J. Malemud 9. Metalloproteinases in Rheumatoid Arthritis: Potential Therapeutic Targets to Improve Current Therapies Yoshifumi Itoh 9. The Roles of Matrix Metalloproteinases in Pancreatic Cancer Anna M. Knapinska, Christie-Anne Estrada and Gregg B. Fields 10. Matrix Metalloproteinase Inhibitors as Investigational and Therapeutic Tools in Unrestrained Tissue Remodeling and Pathological Disorders Jie Liu and Raouf A. Khalil