Main description:

Medicinal Chemistry of Tick-Borne Encephalitis, Volume 58 in the Annual Reports in Medicinal Chemistry serial, highlights new advances in the field, with this new volume presenting interesting chapters on the Discovery of small molecule TBEV antivirals, Perylene as a controversial antiviral scaffold, Animal models of TBEV infection for preclinical studies of drugs and vaccines, Insights from experience in the treatment of tick-borne bacterial co-infections with tick-borne encephalitis, Small molecule-based inhibitors of flaviviral RNA-dependent RNA-polymerase: prospective candidates for treatment of tick-borne encephalitis virus infection, and Structural Biology and Proteomics of Tick-Borne Encephalitis Virus.

Contents:

1. Discovery of small molecule TBEV antivirals Dmitry I. Osolodkin 2. Perylene as a controversial antiviral scaffold Vladimir A. Korshun 3. Animal models of TBEV infection for preclinical studies of drugs and vaccines Daniel Ruzek 4. Insights from experience in the treatment of tick-borne bacterial co-infections with tick-borne encephalitis Nadezhda Kolyasnikova, Jeanna Pavlovna Sanchez-Pimentel and Nikolay Borisovich Pestov 5. Small molecule-based inhibitors of flaviviral RNA-dependent RNA-polymerase: prospective candidates for treatment of tick-borne encephalitis virus infection Katherine L. Seley-Radtke and Ludek Eyer 6. Structural Biology and Proteomics of Tick-Borne Encephalitis Virus Sarah Jane Butcher