Main description:

Mitochondrial medicine deals with diseases that are related to mitochondrial dysfunction due to a number of causes from free radical damage to genetic mutation. This book is based on extensive data gathered over 30 years of clinical and experimental research. In it, internationally recognized authors share their experience in various fields of their expertise and guide readers through the disease process, from basic biochemical mechanisms to diagnosis to therapeutic aspects.

Contents:

Mitochondrial Physiology.- Oxidants, Antioxidants and Oxidative Stress.- Chronobiology, Chronomics and N-of-1 Tests of Timing Coenzyme Q10.- Methods of Chronobiometric Analysis of Mitochondrial Function.- Mitochondrial Medicine.- Mitochondrial Cardiology.- Mitochondria of the Human Transplanted Heart.- Mitochondrial Diabetology.- Mitochondrial Nephrology.- Mitochondrial Bioenergetics of Skeletal Muscles.- Rheumatoid Arthritis.- Mitochondrial Immunology.- Mitochondrial "Spermatopathy".- Methods for Diagnosis of Mitochondrial Diseases.- Nuclear Magnetic Resonance.- Clinical Aspects of Coenzyme Q10 in Relationship with Its Bioenergetic and Antioxidant Properties.- Coenzyme Q10 Supplementation in Clinical Medicine.- Coenzyme Q10 Supplementation in Experimental Medicine.- Omega-3-PUFA, Omega-6-PUFA and Mitochondria.- Carnitine.- Vitamins in Mitochondrial Function.- Polarized Light.