Main description:

Advances in molecular biology over the last several decades are being steadily applied to our understanding of the molecular biology of cancer, and these advances in knowledge are being translated into the clinical practice of oncology. This volume explores some of the most exciting recent advances in basic research on the molecular biology of cancer and how this knowledge is leading to advances in the diagnosis, treatment, and prevention of cancer.

Contents:

1. Introduction to the Molecular Biology of Cancer: Translation to the Clinic
Raymond W. Ruddon
2. Molecular Biology and Anti-cancer Drug Discovery
John S. Lazo
3. Targeting chemokine (C-C motif) ligand 2 (CCL2) as an example of translation of cancer molecular biology to the clinic
Jian Zhang, Lalit Patel, and Kenneth J. Pienta
4. Chromosome Translocations in Solid Tumors
Arul Chinnaiyan and Nallasivam Palanisamy
5. Circulating Tumor Cells
Daniel F. Hayes and Jeffrey B. Smerage
6. Stem Cells in Normal Development and Cancer
Rosemarie Chirco D'Angelo and Max S. Wicha
7. Bioinformatics and Systems Biology of Cancers
Gilbert S. Omenn
8. Progress in Cancer Nanotechnology
James R. Baker, Istvan J. Majoros, Brent B. Ward, Kyung-Hoon Lee, Seok Ki Choi, Baohua Huang, Andrzej Myc
9. Applications of Molecular Imaging
Craig J. Galban, Stefanie Galban, Marcian E. Van Dort, Gary D. Luker, Mahaveer S. Bhojani, Alnawaz Rehemtualla and Brian D. Ross
10. Cancer epigenetic
Wendell Weber
11. Molecular Targets and Clinical Cancer Risk Reductive Interventions
Madhuri Kakarala and Dean E. Brenner