Main description:

Molecular Biology of Neurodegenerative Diseases: Visions for the Future, Part B, Volume 177 in the Progress in Molecular Biology and Translational Science series, provides the most topical, informative and exciting monographs available on a wide variety of research topics. The series includes in-depth knowledge on the molecular biological aspects of organismal physiology, with this release including chapters on Alzheimer's disease, Prion-like propagation of alpha-synuclein, What - if anything - can we learn about neurodegenerative diseases from yeast?, Mitochondrial rejuvenation and replacement as a novel strategy for treatment of age-related neurodegenerative diseases, and more.

Contents:

Preface

David Teplow

1. Relevance of transgenic mouse models for Alzheimer's disease

Leon Tai, Juan Maldonado Weng, Mary Jo LaDu and Scott Brady

2. Mitochondrial transplant to replenish damaged mitochondria: A novel therapeutic strategy for neurodegenerative diseases?

Abhisek Mukherjee, Andrea D Becerra Calixto, Melissa Chavez, Jean Paul Delgado Charris and Claudio Soto

3. Activity-dependent neuroprotective protein (ADNP)-end-binding protein (EB) interactions regulate microtubule dynamics toward protection against tauopathy

Yanina Ivashko-Pachima and Illana Gozes

4. Applying available knowledge and resources to alleviate familial and sporadic neurodegenerative disorders

Mark P. Mattson

5. The cellular machinery of post-endocytic APP trafficking in Alzheimer's disease: A future target for therapeutic intervention?

Lawrence S.B. Goldstein and Utpal Das

6. The search for novel targets in Alzheimer's disease-The 90s redux

Christian Behl

7. Adult hippocampal neurogenesis in Alzheimer's disease

Ahmed Disouky and Orly Lazarov

8. Early detection and personalized medicine: Future strategies against Alzheimer's disease

Antonio Di Meco and Robert Vassar

9. Inflammation and Parkinson's disease pathogenesis: Mechanisms and therapeutic insight

Gianluigi Forloni, Pietro la Vitola, Milica Cerovic and Claudia Balducci