Main description:

Preclinical research related to mood and anxiety disorders relies extensively upon mouse behavioral tests and models, the use of which continues to increase as a greater number of underlying susceptibility genes are discovered, new targets for medications are identified, and clinical studies reveal novel neurobiological risk factors. Mood and Anxiety Related Phenotypes in Mice: Characterization Using Behavioral Tests, Volume II serves as a complement to the previous volume in order to offer a comprehensive resource for the behavioral approaches that are valuable for the characterization of mood and anxiety disorder-related behaviors in mice and the techniques that are utilized in the development of effective medications. As a collection presented in the Neuromethods series, each chapter provides a brief background and review of the test or model as well as a complete and up-to-date protocol narrative.

Authoritative and comprehensive, Mood and Anxiety Related Phenotypes in Mice: Characterization Using Behavioral Tests, Volume II is an ideal resource for scientists actively pursuing or interested in establishing vital behavioral protocols in their laboratories.

Contents:

1. Longitudinal Assessment of Deliberate Mouse Behavior in the Home Cage and Attached Environments: Relevance to Anxiety and Mood Disorders

Martien J. Kas, Ilan Golani, Yoav Benjamini, Ehud Fonio, and Oliver Stiedl

2. Using Behavioral Patterns Across Species in Mood Disorder Research

Jared W. Young and Mark A. Geyer

3. Telemetry in Mice: Applications in Studies of Stress and Anxiety Disorders

Larry D. Sanford, Linghui Yang, and Laurie L. Wellman

4. Modeling Mouse Anxiety and Sensorimotor Integration: Phenotypes in the Suok Test

Elisabeth Dow, Valerie Piet, Adam Stewart, Siddharth Gaikwad, Jonathan Cachat, Peter Hart, Nadine Wu, Evan Kyzar, Eli Utterback, Alan Newman, Molly Hook, Kathryn Rhymes, Dillon Carlos, and Allan V. Kalueff

5. Assessment of Social Approach Behavior in Mice

Orsolya J. Kuti and Damon T. Page

6. The Mouse Defense Test Battery: A Model Measuring Different Facets of Anxiety-Related Behaviors

Guy Griebel and Sandra Beeske

7. Novelty-Suppressed Feeding in the Mouse

Benjamin Adam Samuels and Rene Hen

8. The Four-Plate Test in Mice

14. Emotionality-Related Consequences of Early Weaning in Mice and Rats

Takefumi Kikusui

15. Separation-Induced Depression in the Mouse

Richard E. Brown, Alison L. Martin, and Rhian K. Gunn

16. Induction of Persistent Depressive-Like Behavior by Corticosterone

Shannon L. Gourley and Jane R. Taylor

17. The Olfactory Bulbectomized Mouse

Martine Hascoet and Michel Bourin

9. The Vogel Punished Drinking Task as a Bioassay of Anxiety-Like Behavior of Mice

Alicia A. Walf and Cheryl A. Frye

10. A Vogel Conflict Test Using Food Reinforcement in Mice

Jeffrey M. Witkin

11. Fear Conditioning and Extinction as a Model of PTSD in Mice

Georgette M. Gafford and Kerry J. Ressler

12. The "Cut-off Behavioral Criteria" Method: Modeling Clinical Diagnostic Criteria in Animal Studies of PTSD

14. Emotionality-Related Consequences of Early Weaning in Mice and Rats

Takefumi Kikusui

15. Separation-Induced Depression in the Mouse

Richard E. Brown, Alison L. Martin, and Rhian K. Gunn

16. Induction of Persistent Depressive-Like Behavior by Corticosterone

Shannon L. Gourley and Jane R. Taylor

17. The Olfactory Bulbectomized Mouse

Cohen Hagit, Michael A. Matar, and Zohar Joseph

13. Measuring Variations in Maternal Behavior: Relevance for Studies of Mood and Anxiety

Becca Franks, James P. Curley, and Frances A. Champagne

Michelle Roche

18. Differential-Reinforcement-of-Low-Rate Behavior in Rodents as a Screen for Antidepressant Efficacy

Lindsay M. Lueptow and James M. O'Donnell

19. The Intracranial Self-Stimulation Procedure Provides Quantitative Measures of Brain Reward Function

Astrid K. Stoker and Athina Markou

20. The Female Urine Sniffing Test (FUST) of Reward Seeking Behavior

Oz Malkesman

21. Measuring Impulsive Choice Behaviour in Mice

Claire L. Dent and Anthony R. Isles

22. Assessment of Male Sexual Behavior in Mice

Jin Ho Park

14. Emotionality-Related Consequences of Early Weaning in Mice and Rats

Takefumi Kikusui

15. Separation-Induced Depression in the Mouse

Richard E. Brown, Alison L. Martin, and Rhian K. Gunn

16. Induction of Persistent Depressive-Like Behavior by Corticosterone

Shannon L. Gourley and Jane R. Taylor

17. The Olfactory Bulbectomized Mouse

Michelle Roche

18. Differential-Reinforcement-of-Low-Rate Behavior in Rodents as a Screen for Antidepressant Efficacy

Lindsay M. Lueptow and James M. O'Donnell

19. The Intracranial Self-Stimulation Procedure Provides Quantitative Measures of Brain Reward Function

Astrid K. Stoker and Athina Markou

20. The Female Urine Sniffing Test (FUST) of Reward Seeking Behavior

Oz Malkesman

21. Measuring Impulsive Choice Behaviour in Mice

Claire L. Dent and Anthony R. Isles

22. Assessment of Male Sexual Behavior in Mice

Jin Ho Park