Main description:

Unique and timely volume as mRNA is a hot area of research making great strides.

Covers the full-scale production systems that are needed to develop vaccines as well as elements of data needed to secure the IND approvals.

Introduces a commercial-scale manufacturing process using novel techniques like the PCR, in addition to the traditional plasmid DNA.

First book that offers commercial technology for developing and large-scale supply of mRNA products.

Renowned author and entrepreneur in the field of drug discovery and production.

Contents:

Background. 1. The Genome Machine. 2. Understanding Nucleic Acids. 3. RNA Therapeutics. 4. Nucleoside Vaccines. 5. cGMP mRNA Vaccine Manufacturing. 6. Regulatory Guidance. Appendix 1. Covid-19 mRNA Vaccine Manufacturing Feasibility. Appendix 2. Pharmacopeial Testing. Appendix 3. Suggested Readings