Main description:

This book covers intentional design aspects for combinations of drugs, single-molecule hybrids with potential or actual multiple actions, pro-drugs which could yield multiple activity outcomes, and future possibilities. The approach of the book is interdisciplinary, and it provides greater understanding of the complex interplay of factors involved in the medicinal chemistry design and laboratory development of multiply active antibacterials. The scope of the book appeals to readers who are researching in the field of antibacterials using the approach of medicinal chemistry design and drug development.

Contents:

Introduction to Antibacterials.- Antibacterial Combinations.- Single Molecule Non-cleavable Multiply Active Antibacterials.- Design Principles and Development of Multiply Active Pro-drug Antibacterials.- Future Possibilities.