Main description:

This is a comprehensive, state-of-the-art guide to the diagnosis, treatment, and biology of multiple myeloma and related plasma disorders. Edited and written by a multidisciplinary group of recognized authorities from the Mayo Clinic, it presents clear guidelines on diagnosis and therapy and covers all aspects of multiple myeloma, from molecular classification and diagnosis, to risk stratification and therapy. Closely related plasma cell disorders such as solitary plasmacytoma, Waldenstrom macroglobulinemia, and light chain amyloidosis are discussed in detail as well. The book addresses often overlooked topics, including the role of radiation therapy, vertebral augmentation, and supportive care.

Our understanding of this group of disorders is developing at an unprecedented rate, and Multiple Myeloma meets the need among oncologists and hematologists for a clear, timely, and authoritative resource on their biology, diagnosis, and treatment.

Contents:

Chapter 1

Criteria for Diagnosis & Response

Robert A. Kyle, M. D. and S. Vincent Rajkumar, M. D.

Chapter 2

Detection of M proteins

Jerry A. Katzmann, Ph.D.

Chapter 3

Pathology Of Multiple Myeloma

Dragan Jevremovic, M.D., Ph.D., and William Morice, M.D., Ph.D.

Chapter 4

Pathogenesis of Multiple Myeloma

Marta Chesi, PhD and P. Leif Bergsagel, MD

Chapter 5

Staging of Multiple Myeloma

Vivek Roy, M.D. and Philip R. Greipp, M.D

Chapter 6

Molecular Classification and Risk Stratification

Shaji Kumar, M.D, Rafael Fonseca, M.D., Keith Stewart, MB. ChB.

Chapter 7

Monoclonal Gammopathies of Undetermined Significance and Smoldering Multiple Myeloma

John A. Lust, MD, PhD, Diane F. Jelinek, PhD, Kathleen A. Donovan, PhD

Chapter 8

Treatment of Newly Diagnosed Multiple Myeloma

Shaji K. Kumar, M.D., Steven J Russell, M.D., Ph.D

Chapter 9

Approach to Relapsed Refractory Myeloma

Joseph Mikhael, MD, Shaji Kumar, MD, S. Vincent Rajkumar, MD

Chapter 10

Autologous Stem Cell Transplantation in the Management of Multiple Myeloma

Morie A. Gertz, M.D., M.A.C.P., Craig B. Reeder, M.D

Chapter 11

Allogeneic Stem Cell Transplantation

Martha Q. Lacy M. D.

Chapter 12

New Agents For Multiple Myeloma

Shaji Kumar, M.D., Arleigh McCurdy, M.D.

Chapter 13

Biological Therapy for Multiple Myeloma

Camilo Ayala-Breton, Stephen J Russell, Kah-Whye Peng

Chapter 14

Management of Treatment Complications and Supportive Care

Francis Buadi, MB. ChB and Asher Chanan Khan, MD

Chapter 15

POEMS Syndrome (Takatsuki Syndrome)

Angela Dispenzieri

Chapter 16

SOLITARY PLASMACYTOMA

David Dingli, MD, PhD and Prashant Kapoor, MD

Chapter 17

Myeloma Bone Disease

Matthew T. Drake, MD, Ph.D

Chapter 18

Vertebral Augmentation

Omar Khan, M.D. and David Kallmes, M.D.

Chapter 19

The Role of Radiation Therapy in the Treatment of Multiple Myeloma, Plasmacytoma and Other Plasma Cell Disorders

Prashant Kapoor, M.D., James A. Martenson, M.D

Chapter 20

Neurologic Complications of Myeloma

Chafic Y. Karam M.D., Michelle L. Mauermann M.D

Chapter 21

Myeloma Cast Nephropathy

Nelson Leung, MD

Chapter 22

Amyloidosis

Morie A. Gertz, M.D., Steven R. Zeldenrust, M.D., Ph.D.

Chapter 23

IgM Multiple Myeloma

Steven R. Schuster MD, Joseph Mikhael MD

Chapter 24

Waldenstroem's macroglobulinemia

Stephen M. Ansell, Lucy S. Hodge, Suzanne R. Hayman