Main description:

Neglected Diseases: Extensive Space for Modern Drug Discovery provides in-depth reviews on the last progresses about neglected tropical diseases research. Topics covered in this volume include Leishmaniasis, Tripanosomiasis, Onchocerciasis and Ebolavirus infections, with insights on the future of the research on them. Part of the volume is devoted to recent contributions this field received from X-Ray crystallography.

Contents:

1. Targeting Human Onchocerciasis: Recent Advances Beyond Ivermectin Stefano Sainas, Franco Dosio, D. Boschi and M.L. Lolli 2. Scaffolds and Biological Targets Avenue to Fight Against Drug Resistance in Leishmaniasis Chiara Borsari, Antonio Quotadamo, Stefania Ferrari, A. Venturelli, Anabela Cordeiro, Nuno Santarem and Maria Paola Costi 3. Drugs and Drug Resistance in African and American Trypanosomiasis Jaime Franco, Laura Scarone and Marcelo A. Comini 4. Antiviral Agents Against Ebola Virus Infection: Repositioning Old Drugs and Finding Novel Small Molecules Elisa Fanunza, Aldo Frau, Angela Corona and Enzo Tramontano 5. X-Ray Crystallography Contributions to Drug-Discovery Against Parasite Infections Cecilia Pozzi, Giusy Tassone and Stefano Mangani