Main description:

Nucleic Acid Sensing and Immunity - PART A, Volume 344, provides a comprehensive overview of the nucleic acid machinery, from plants to mammalians, as well as their regulation. Specific chapters in this updated release include Molecular bases of discrimination between self from non-self nucleic acids, Intracellular RNA sensing in mammalian cells, Nuclear DNA damage and nucleic acid sensing, Negative regulation of nucleic acid sensing, Dendritic cell responses to exogenous nucleic acids, Activating the nucleic acid-sensing machinery for anticancer immunity, and Nucleic acid sensing and inflammasomes, amongst other topics.

Contents:

1. Molecular bases of discrimination between self from non-self nucleic acids Taro Kawai 2. Intracellular RNA sensing in mammalian cells Nikolai Khodarev 3. Nuclear DNA damage and nucleic acid sensing Fabrizio Ensoli 4. Negative regulation of nucleic acid sensing Sagi Shapira 5. Dendritic cells responses to exogenous nucleic acids Stefania Gallucci 6. Activating the nucleic acid-sensing machinery for anticancer immunity Michael Gough 7. Nucleic acid sensing and inflammasomes Paras Anand