Main description:

This special volume of Progress in Molecular Biology and Translational Science focuses on oligomerization in health and disease.

Contents:

Section I. Structural, Physico-Chemical, and Evolutionary Aspects of Protein Oligomerization

Evolutionary, Physico-Chemical and Functional Mechanisms of Protein Homooligomerization
Structural, Evolutionary and Assembly Principles of Protein Oligomerization
Physico-Chemical Principles of Protein Aggregation
Structural Aspects of Amyloid Formation
Section II. Oligomerization in Seven-Transmembrane Receptors

Quaternary Structure Predictions and Structural Communication Features of GPCR Dimers
Challenges in the Development of Heteromer-GPCR-Based Drugs
Oligomerization of GPCRs in Health and Disease on "Di/Oligomerisation of GPCRS; Mechanisms and Functional Significance"
G Protein-Coupled Receptor Heterocomplexes in Neuropsychiatric Disorders
Disease-Specific Heteromerization of G Protein-Coupled Receptors that Target Drugs of Abuse
Section III. Oligomerization in Ion Channels

Social Networking among Voltage-Gated Potassium Channels
Oligomerization of the Mitochondrial Protein VDAC1: From Structure to Function and Cancer Therapy
Consequences of Dimerization of the Voltage Gated Proton Channel
Receptor Heteromeric Assembly, How it Works and Why it Matters - The Case of Ionotropic Glutamate Receptors
Section IV. Oligomerization in Enzymes

The Structural Basis for the Allosteric Regulation of Ribonucleotide Reductase
Oligomerization of Dynamin Superfamily Proteins in Health and Disease
Multimerization of the Dnmt3a DNA Methyltransferase and its Functional Implications
Oligomerization in Endoplasmic Reticulum Stress Signaling
Section V. Oligomerization in Regulatory Proteins

Toll-IL-1-Receptor-Containing Adaptor Molecule-1 (TICAM-1), a Signaling Adaptor Linking Innate Immunity to Adaptive Immunity
Assembly of Gamma-Tubulin Ring Complexes: Implications for Cell Biology and Disease
Chemokine Oligomerization in Cell Signaling and Migration
Oligomerization of Rab/Effector Complexes in the Regulation of Vesicle Trafficking