This is the Eighth Edition of the comprehensive and well-respected text and reference of pathophysiology. As a nurse-physiologist, Carol Porth uniquely emphasizes "concepts" of altered health states, as opposed to factual descriptions of diseases and disorders. By taking this physiologic approach, the author ensures a comprehension of the whole of body function and both the physical and psychological aspects of altered health.

This edition has a completely revamped art program and new displays that showcase pathophysiological processes though detailed visual representation. Other highlights include a greater international focus, expanded content on evidence-based practice and completely revised, updated chapters on genetics, disorders of white blood cells and lymphoid tissues, and innate and acquired immunity.

Unit I Concepts of Health and Disease

• Chapter 1 Concepts of Health and Disease
• Chapter 2 Concepts of Altered Health in Children-Judy Lott
• Chapter 3 Concepts of Altered Health in Older Adults-Janice Pikna

• Chapter 4 Cell and Tissue Characteristics-Ed Carroll
• Chapter 5 Cellular Adaptation, Injury, and Death -Carrie Merkle
• Chapter 6 Genetic Control of Cell Function and Inheritance -Ed Carroll
• Chapter 7 Genetic and Congenital Disorders
• Chapter 8 Neoplasia -Carrie Merkle and Kerry Twitt

• Chapter 9 Stress and Adaptation-Mary Pat Kunert
• Chapter 10 Alterations in Temperature Regulation-Mary Pat Kunert
• Chapter 11 Activity Tolerance and Fatigue -Mary Kay Jiricka

• Chapter 12 Blood Cells and the Hematopoietic System - Kathryn Gaspard
• Chapter 13 Disorders of Hemostasis -Kathryn Gaspard
• Chapter 14 Disorders of Red Blood Cells -Kathryn Gaspard
• Chapter 15 Disorders of White Blood Cells and Lymphoid Tissues -Keri Twitte

• Chapter 16 Mechanisms of Infectious Disease -W. Michael Dunne, Jr. and Nathan A. Ledeboer
• Chapter 17 Innate and Acquired Immunity -Cynthia Sommer
• Chapter 18 Inflammation and Wound Healing -Cynthia Sommer and Carol Porth
• Chapter 19 Disorders of the Immune Response
• Chapter 20 Acquired Immunodeficiency Syndrome -Jason Faulhaber and Judith A. Aberg

• Chapter 21 Structure and Function of the Cardiovascular System
• Chapter 22 Disorders of Blood Flow in the Systemic Circulation -Glenn Matfin
• Chapter 23 Disorders of Blood Pressure Regulation
• Chapter 24 Disorders of Cardiac Function -Toni Ballistrieri and Kathy Mussato
• Chapter 25 Disorders of Cardiac Conduction and Rhythm -Jill Winters
• Chapter 26 Heart Failure and Circulatory Shock -Anna Barkman and Charlotte Pooler

• Chapter 27 Structure and Function of the Respiratory System -Carol Porth and Kim Litwack
• Chapter 28 Respiratory Tract Infections, Neoplasms, and Childhood Disorders
• Chapter 29 Disorders of Ventilation and Gas Exchange -Charlotte Pooler

• Chapter 30 Structure and Function of the Kidney
• Chapter 31 Disorders of Fluid and Electrolyte Balance -Glenn Matfin and Carol Porth
• Chapter 32 Disorders of Acid-Base Balance -Carol Porth and Kim Litwack
• Chapter 33 Disorders of Renal Function
• Chapter 34 Acute Renal Failure and Chronic Kidney Disease
• Chapter 35 Disorders of Bladder and Lower Urinary Tract

• Chapter 36 Structure and Function of the Gastrointestinal System
• Chapter 37 Disorders of Gastrointestinal Function
• Chapter 38 Disorders of Hepatobiliary and Exocrine Pancreas Function

Unit X Disorders of Endocrine Function

Unit XI Disorders of Genitourinary and Reproductive Function

Unit XII Neural Function

Unit XIII Disorders of Special Sensory Function

Answers to Review Exercises (May be placed on thePoint) Lab Values

Glossary

Note:TOC as of 10-27, truncated