Main description:

A periprosthetic joint infection occurs when bacteria or other foreign organisms enter a wound during or at any point following joint replacement surgery, sometimes even years after surgery. An infection can cause the joint to be painful or cause the implant to loosen, sometimes resulting in the need for revision surgery (Science Daily).

Written by a recognised author and editor team led Philadelphia-based by Javad Parvizi, this practical guide offers advice on the management of surgical site infections following orthopaedic procedures.

Divided into five sections, this new edition covers basics of infection, preoperative medical optimisation, intraoperative and postoperative optimisation, diagnosis of infection, and treatment of periprosthetic joint infection.

The second edition has been fully revised and new topics added to provide orthopaedic surgeons with the latest advances in the field.

Editor, Javad Parvizi, was vice chair of the work group for The Diagnosis of Periprosthetic Joint Infections of the Hip and Knee Guideline and Evidence Report, adopted by the AAOS in 2010.

Key points

Practical guide to management of surgical site infections following orthopaedic procedures
Fully revised second edition with new topics added
Recognised editor and author team led by Philadelphia-based Javad Parvizi
Previous edition (9789350902714) published in 2013

Contents:

Section 1: Basics of Infection

Definition of Periprosthetic Joint Infections
Incidence and Burden of Periprosthetic Joint Infection
Economic Burden of Periprosthetic Joint Infection
Common Antibiotics and Mechanism of Action
Biofilm
Multidisciplinary Approach to Management of Periprosthetic Joint Infections
Future Trends and Challenges

Section 2: Preoperative Medical Optimization

Predisposing Factors for Periprosthetic Joint Infection
Perioperative Management of Diabetes Mellitus and Hyperglycemia
Malnutrition and Obesity
Cigarette and Tobacco Risks
Prior Intra-articular Joint Injection and Risk of Infection
Perioperative Management of Home Medications and Supplements
Inflammatory Arthropathy
Total Joint Arthroplasty in Patients with Prior Septic Arthritis
Perioperative Management of Concomitant Infections
Conversion Arthroplasty with Hardware in Situ
Liver and Kidney Disease
Anemia
Peripheral Vascular Disease
Alcohol and Drug Use
Depression and Other Psychiatric Illnesses
Anticoagulation and Prosthetic Joint Infection
Infection Prevention Guidelines

Section 3: Intraoperative and Postoperative Optimization

Preoperative Skin Preparation: Decolonization and Antisepsis
Operating Room Environment
Incise Drapes
Antibiotic Prophylaxis
Workup of Patients with Suspected Urinary Tract Infection
Irrigation Solutions in Total Joint Arthroplasty
Cement and Antibiotics
Blood Conservation
Wound Closure and Drain Use
Postarthroplasty Antibiotic Prophylaxis

Section 4: Diagnosis of Infection

Available Diagnostic Laboratory Tests and Molecular Biomarkers
Joint Aspiration
Imaging for Diagnosis of Periprosthetic Joint Infection
Culture Principles
Culture-negative Periprosthetic Joint Infections
Diagnosis of Periprosthetic Joint Infection in Inflammatory Conditions
Diagnosis of Periprosthetic Joint Infection in Adverse Metal Reaction
Diagnosing Periprosthetic Joint Infection: The Rothman Institute Algorithm

Section 5: Treatment of Periprosthetic Joint Infection

Management of Wound Drainage
Management of Fungal Periprosthetic Joint Infections
Management of Mycobacterial Infection
Management of Periprosthetic Joint Infection Caused by Enterococcus
Periprosthetic Joint Infection Caused by Rare Organisms
Irrigation and Debridement for Periprosthetic Joint Infection
One-stage Exchange Arthroplasty for Periprosthetic Joint Infection
Resection Arthroplasty
Removal of Well-fixed Hip and Knee Arthroplasty Components in the Setting of Periprosthetic Joint Infection
Two-stage Exchange Arthroplasty: Antibiotic Spacers
Reimplantation Following Two-stage Exchange Arthroplasty for Prosthetic Joint Infection
Suppressive Antimicrobial Therapy and Prosthetic Joint Infection
Prognostic Classification for Periprosthetic Joint Infection
Periprosthetic Joint Infection and Mortality
Current Limitations, Evolving Technologies and Future Directions in the Management of Periprosthetic Joint Infection

Index