Main description:

A comprehensive collection of robust methods for the detection of pesticide compounds or their metabolites useful in food, environmental, and biological monitoring, and in studies of exposure via food, water, air, and the skin or lungs. The readily reproducible methods range from gas and liquid chromatography coupled to mass spectrometry detection and other classic detectors, to capillary electrophoresis and immunochemical or radioimmunoassay methods. The authors have focused on extraction and cleanup procedures, in order to develop and optimize more fullyautomated and miniaturized methods, including solid-phase extraction, solid-phase microextraction, microwave-assisted extraction, and on-line tandem liquid chromatography (LC/LC) trace enrichment, among others. The protocols offer step-by-step laboratory instructions, an introduction outlining the principles behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.

Contents:

Part I. Analytical Methodologies to Determine Pesticides and Metabolites in Human Fat Tissues and Body Fluids

Analysis of Endocrine Disruptor Pesticides in Adipose Tissue Using Gas Chromatography-Tandem Mass Spectrometry: Assessment of the Uncertainty of the Method
Jose L. Martinez Vidal, Antonia Garrido Frenich, Francisco J. Egea Gonzalez, and Francisco J. Arrebola Liebanas

Determination of Pyrethroids in Blood Plasma and Pyrethroid/Pyrethrin Metabolites in Urine by Gas Chromatography-Mass Spectrometry and High-Resolution GC-MS
Gabriele Leng and Wolfgang Gries

A Multianalyte Method for the Quantification of Current-Use Pesticides in Human Serum or Plasma Using Isotope Dilution Gas Chromatography-High-Resolution Mass Spectrometry
Dana B. Barr, Roberto Bravo, John R. Barr, and Larry L. Needham

Application of Solid-Phase Disk Extraction Combined With Gas Chromatographic Techniques for Determination of Organochlorine Pesticides in Human Body Fluids
Adrian Covaci

A Comprehensive Approach for Biological Monitoring of Pesticides in Urine Using HPLC-MS/MS and GC-MS/MS
Dana B. Barr, Anders O. Olsson, Roberto Bravo, and Larry L. Needham

Urinary Ethylenethiourea as a Biomarker of Exposure to Ethylenebisdithiocarbamates
Silvia Fustinoni, Laura Campo, Sarah Birindelli, and Claudio Colosio

Analysis of 2,4-Dichlorophenoxyacetic Acid and 2-Methyl-4- Chloro-Phenoxyacetic Acid in Human Urine
Cristina Aprea, Gianfranco Sciarra, Nanda Bozzi, and Liana Lunghini

Determination of Herbicides in Human Urine by Liquid Chromatography-Mass Spectrometry With Electrospray Ionization
Isabel C. S. F. Jardim, Joseane M. Pozzebon, and Sonia C. N. Queiroz

Analysis of Pentachlorophenol and Other Chlorinated Phenols in Biological Samples by Gas Chromatography or Liquid Chromatography-Mass Spectrometry
Ji Y. Zhang

Analysis of2,4-Dichlorophenoxyacetic Acid in Body Fluids of Exposed Subjects Using Radioimmunoassay
Dietmar Knopp

A High-Throughput Screening Immunochemical Protocol for Biological Exposure Assessment of Chlorophenols in Urine Samples
Mikaela Nichkova and M.-Pilar Marco

Part II. Assessment of Inhalatory and Potential Dermal Exposure

Assessment of Postapplication Exposure to Pesticides in Agriculture
Joop J. van Hemmen, Katinka E. van der Jagt, and Derk H. Brouwer

Field Study Methods for the Determination of Bystander Exposure to Pesticides
C. Richard Glass

Determination of Household Insecticides in Indoor Air by Gas Chromatography-Mass Spectrometry
Edith Berger-Preiss and Lutz Elflein

Assessment of Dermal and Inhalatory Exposure of Agricultural Workers to Malathion Using Gas Chromatography-Tandem Mass Spectrometry
Francisco J. Egea Gonzalez, Francisco J. Arrebola Liebanas, and A. Marin

Pesticides in Human Fat and Serum Samples vs Total Effective Xenoestrogen Burden
Patricia Araque, Ana M. Soto, M. Fatima Olea-Serrano, Carlos Sonnenschein, and Nicolas Olea

Part III. Pesticide Analysis in Food

Quality Criteria in Pesticide Analysis
Antonia Garrido Frenich, Jose L. Martinez Vidal, Francisco J. Egea Gonzalez, and Francisco J. Arrebola Liebanas

Immunoassay Methods for Measuring Atrazine and 3,5,6-Trichloro-2-Pyridinol in Foods
Jeanette M. Van Emon and Jane C. Chuang

Quick, Easy, Cheap, Effective, Rugged, and Safe Approach for Determining Pesticide Residues
Steven J. Lehotay

Determination of Organophosphorus Pesticide Residues in Vegetable Oils by Single-Step Multicartridge Extraction and Cleanup and by Gas Chromatography With Flame Photometric Detector
Alfonso Di Muccio, Anna M. Cicero, Antonella Ausili, and Stefano Di Muccio

Multiclass Pesticide Analysis in Vegetables Using