Main description:

Pharmaceutical Preformulation and Formulation: A Practical Guide from Candidate Drug Selection to Commercial Dosage Form reflects the mounting pressure on pharmaceutical companies to accelerate the new drug development and launch process, as well as the shift from developing small molecules to the growth of biopharmaceuticals. The book meets the need for advanced information for drug preformulation and formulation and addresses the current trends in the continually evolving pharmaceutical industry.

Topics include:

Candidate drug selection
Drug discovery and development
Preformulation predictions and drug selections
Product design to commercial dosage form
Biopharmaceutical support in formulation
Development

The book is ideal for practitioners working in the pharmaceutical arena-including R&D scientists, technicians, and managers-as well as for undergraduate and postgraduate courses in industrial pharmacy and pharmaceutical technology.

Contents:

Topical and Transdermal Drug Delivery. Introduction and Perspective. Aiding Candidate Selection: Introduction and Objectives. Preformulation Predictions. Biopharmaceutical Support in Candidate Drug Selection. Early Product Development. Preformulation as an aid to Product Design in Early development. Biopharmaceutics Support to Formulation development. Biopharmaceutics Support to Formulation development. Product Optimisation. Parenteral dosage Forms. Inhalation dosage Forms. Oral Solid Dosage Forms. Ophthalmic Dosage Forms. Aqueous Nasa Dosage Forms. Topical and Transdermal Drug Delivery.