Main description:

This volume has a strong focus on homo-oligomerization, which is surprisingly common. However, protein function is so often linked to both homo- and hetero-oligomerization and many heterologous interactions likely evolved from homologous interaction, so this volume also covers many aspects of hetero-oligomerization.

Contents:

Dimers, Oligomers, Everywhere.- The Detection and Quantitation of Protein Oligomerization.- Computational and Structural Characterisation of Protein Associations.- Death by Caspase Dimerization.- The Relationship between Oligomeric State and Protein Function.- Oligonucleotide Binding Proteins: The Occurrence of Dimer and Multimer Formation.- Homo- and Heterodimerization in Transcriptional Regulation.- OligomeriZation at the Membrane: Potassium Channel Structure and Function.- Implications of 3D Domain Swapping for Protein Folding, Misfolding and Function.- From artificial antibodies to nanosprings: The biophysical properties of repeat proteins.