Main description:

This volume explores some of the most exciting recent advances in basic research on protein phosphorylation in health and disease and how this knowledge is leading to advances in the various fields.

Contents:

Wip1 -dependent signaling pathways in health and diseases Yun-hua Zhu and Dmitry V. Bulavin
HijAkt: The PI3k/Akt pathway in virus replication and pathogenesis Ewan F. Dunn and John H. Connor
Phosphoproteins in stress-induced disease Lucy E. Dalton, Eleanor Healey, James Irving & Stefan J. Marciniak
G-substrate: The Cerebellum and Beyond Shogo Endo
Targeting Phosphorylation of Eukaryotic Initiation Factor-2a to Treat Human Disease Melissa J. Fullwood, Wei Zhou and Shirish Shenolikar
Signaling in striatal neurons: the phosphoproteins of reward, addiction, and dyskinesia Jean-Antoine Girault
The Role of Protein Phosphorylation in Therapy-resistance and Disease Progression in Chronic Myelogenous Leukemia Wen Chun JUAN and S. Tiong ONG
Phosphatases driving mitosis: pushing the gas and lifting the brakes Erika Segear Johnson and Sally Kornbluth
Protein tyrosine phosphatases in cancer: Friends and Foes David P. Labbe, Serge Hardy, Michel L. Tremblay
Multiple Roles Of Stat3 In Cardiovascular Inflammatory Responses Cheh Peng Lim and Xin-Yuan Fu
PAKs in human disease Perry M. Chan and Ed Manser
Protein Phosphatases and Alzheimer's Disease Steven P. Braithwaite, Jeffry B. Stock, Paul J. Lombroso, Angus C. Nairn
Role of the JNK pathway in human diseases Kanaga Sabapathy
Mass spectrometric tools for systematic analysis of protein phosphorylation Nicole St-Denis1 and Anne-Claude Gingras