Feature:

Describes fundamental aspects of protein adsorption to surfaces

Presents methods for studying adsorption kinetics and conformational changes such as optical waveguide lightmode spectroscopy

Includes a model study of fibronectin at polymer surfaces

Also addresses biocompatibility, anti-fouling properties and surface modification to modulate the adsorption and activity of biomolecules

Contents:

Analysis of the Adsorption Kinetics.- Protein Adsorption Kinetics: Influence of Substrate Electric Potential.- From Kinetics to Structure: High Resolution Molecular Microscopy.- Initial Adsorption Kinetics in a Rectangular Thin Channel, and Coverage-Dependent Structural Transition Observed by Streaming Potential.- Analysis of the Structure at the Interface.- Dual Polarisation Interferometry: An Optical Technique to Measure the Orientation and Structure of Proteins at the Solid-Liquid Interface in Real Time.- Total Internal Reflection Ellipsometry: Monitoring of Proteins on Thin Metal Films.- Conformations of Proteins Adsorbed at Liquid-Solid Interfaces.- Evaluation of Proteins on Bio-Devices.- Some Applications.- Fibronectin at Polymer Surfaces with Graduated Characteristics.- Development of Chemical Microreactors by Enzyme Immobilization onto Textiles.- Approaches to Protein Resistance on the Polyacrylonitrile-based Membrane Surface: an Overview.- Modulation of the Adsorption and Activity of Protein/Enzyme on the Polypropylene Microporous Membrane Surface by Surface Modification.- Nonbiofouling Surfaces Generated from Phosphorylcholine-Bearing Polymers.