Published October, 2012
By Wolfgang Loscher and Wolfgang Loescher
Publisher: Springer (Birkhauser Verlag AG)
Series: Milestones in Drug Therapy
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In this volume on valproate emphasis is placed on the scientific back ground leading to the discovery of val pro ate, its subsequent pharmacologi cal and toxicological characterization, and its clinical development into one of the most widely and successfully used anti epileptic drugs, a real mile stone in drug therapy.

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Published October, 2012
By B.M. Weichman, A.J. Main and L. Marshall
Publisher: Springer (Birkhauser Verlag AG)
Series: Agents and Actions Supplements
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The Eighth International Conference of the Inflammation Research Association was held on October 27 to 31, 1996 at Hershey Lodge and Convention Center in Hershey, Pennsylvania.

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Published October, 2012
By Vincent C. Hascall and Klaus E. Kuettner
Publisher: Springer (Birkhauser Verlag AG)
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Osteoarthritis is the most common joint pathology which primarily affects the older population. The disease is characterized by unique pathological changes in some synovial joints, predominantly affecting the articular cartilage, but also entire joints, including the synovial tissue and subchondral bone.

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Published October, 2012
By Paul G. Winyard, David R. Blake, Christopher H. Evans and Paul Winyard
Publisher: Springer (Birkhauser Verlag AG)
Series: Progress in Inflammation Research
Rating: 0.00
Availability: Available

Whilst systems such as these to a mathematician would provide the basis for a chaotic response, one is forced to marvel how, for all stages of an inflammatory reaction, this system appears exquisitely controlled, making therapeutic manipula tion both possible and, to some extent, predictable.

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Published October, 2012
By R.W. Wilmott and Robert Wilmott
Publisher: Springer (Birkhauser Verlag AG)
Series: Respiratory Pharmacology and Pharmacotherapy
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Availability: Available

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Published October, 2012
By Miriam Lehrer
Publisher: Springer (Birkhauser Verlag AG)
Series: Experientia Supplementum
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Availability: Available

Many arthropods use celestial (skylight) and terrestrial (magnetic) compass cues for orientation, and some of them were shown to develop, through experience, oriented behaviours based on a variety of innate, hard-wired orientation mechanisms.

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Published October, 2012
By Kevin M.K. Bottomley, David Bradshaw and John S. Nixon
Publisher: Springer (Birkhauser Verlag AG)
Series: Progress in Inflammation Research
Rating: 0.00
Availability: Available

This volume describes recent research in the field of metalloproteinases (a family of enzymes that can catalyze tissue degradation), in particular their participation in autoimmune diseases such as rheumatoid arthritis, reviewing the latest developments in metalloproteinase inhibitor design and the current status of clinical candidates.

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Published October, 2012
By S.D. Brain, P.K. Moore and Susan Brain
Publisher: Springer (Birkhauser Verlag AG)
Series: Progress in Inflammation Research
Rating: 0.00
Availability: Available

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Published October, 2012
By H. Redl
Publisher: Springer (Birkhauser Verlag AG)
Series: Progress in Inflammation Research
Rating: 0.00
Availability: Available

The importance of this cytokine release is evident from both diagnostic and thera peutic (mostly experimental) studies, and the action of cytokines may be the key to our understanding of the pathophysiology of the sepsis syndrome.

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Published October, 2012
By K. Bijlsma, V. Loeschke and Volker Loeschcke
Publisher: Springer (Birkhauser Verlag AG)
Series: Experientia Supplementum
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Availability: Available

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