Published December, 2010
By Vinata B. Lokeshwar, Axel S. Merseburger and Stefan H. Hautmann
Publisher: Springer (Humana Press Inc.)
Series: Cancer Drug Discovery and Development
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Clinical management of bladder cancer is challenging because of the heterogeneity among bladder tumors with respect to invasion and metastasis, frequent occurrence of new tumors in the bladder among patients treated with bladder preservation treatments and poor prognosis of patients with tumors that invade the bladder muscle and beyond.

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Published December, 2010
By Horst Gert J. Ter and Gert J. Ter Horst
Publisher: Springer (Humana Press Inc.)
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These distinguished authorities critically review what is known about autonomic control of the heart, hypothalamo-pituitary- adrenal modulation, heart pain, modulation by humoral factors, and the relationship between cognitive/neuropsychiatric disorders and heart disease.

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Published December, 2010
By Giuseppe Di Giovanni, Ennio Esposito and Vincenzo Di Matteo
Publisher: Springer (Humana Press Inc.)
Series: The Receptors
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Part of Springer's "The Receptors," series, this text is the first ever overview on the research of 5-HT2c receptors. 5-HT2c is a prominent central serotonin receptor subtype widely expressed within the central and the peripheral nervous system and is thought to play a key role in the regulation of numerous behaviors.

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Published December, 2010
By Giampietro Gasparini and Daniel F. Hayes
Publisher: Springer (Humana Press Inc.)
Series: Cancer Drug Discovery and Development
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Availability: Available

Among the topics discussed are the relevance of rigorous study design and guidelines for the validation studies of new biomarkers, gene expression profiling by tissue microarrays, adjuvant systemic therapy, and the use of estrogen, progesterone, and epidermal growth factor receptors as both prognostic and predictive indicators.

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Published December, 2010
By Kevin Strange
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Availability: Available

Molecular biology has driven a powerful reductionist, or "molecule-c- tric," approach to biological research in the last half of the 20th century. Systems biology is integrative and seeks to understand and predict the behavior or "emergent" properties of complex, multicomponent biological processes.

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Published December, 2010
By Peter Paul de Deyn and Debby van Dam
Publisher: Springer (Humana Press Inc.)
Series: Neuromethods
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With an ever-increasing elderly population and the resultant rising levels of dementia-related disorders, preclinical research based on animal models is pivotal to our knowledge of underlying molecular mechanisms and drug discovery aiming at the development of therapeutic strategies alleviating or preventing the neurological devastation.

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Published December, 2010
By Philip Hornick
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Leading clinicians and scientists in solid organ transplantation review the current status of the field and describe cutting-edge techniques for detecting the immune response to the allografted organ.

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Published December, 2010
By Maurie Markman and Lorenzo Cohen
Publisher: Springer (Humana Press Inc.)
Series: Current Clinical Oncology
Rating: 0.00
Availability: Available

Integrative medicine strives to incorporate the best of complementary and conventional modalities. It examines five prestigious, comprehensive cancer centers based in the US, covering how these centers started their programs, what they are currently doing, and recommendations for starting integrative medicine clinics.

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Published December, 2010
By Sharon Marsh
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Availability: Available

This book presents detailed protocols for the multidisciplinary application of Pyrosequencing (R) technology, all written by world-renowned experts. This comprehensive volume enables quick reference by collecting the primary applications for Pyrosequencing (R), and supplementing each protocol with troubleshooting tips specific to that method.

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Published December, 2010
By Lakshmi A. Devi
Publisher: Springer (Humana Press Inc.)
Series: Contemporary Clinical Neuroscience
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Availability: Available

Also discussed are the most recent developments that could lead to new drug discoveries: the role of GPCRs in mediating pain, the development of receptor-type selective drugs based on the structural plasticity of receptor activation, and the identification of natural ligands of orphan GPCRs (deorphanization) as possible drug targets.

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