Published November, 2010
By John R. Gosden
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Chromosomes, as the genetic vehicles, provide the basic material for a large proportion of genetic investigations, from the construction of gene maps and models of chromosome organization, to the inves tigation of gene function and dysfunction.

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Published November, 2010
By Robin Martin
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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The synthesis of proteins from 20 or so constituent amino acids according to a strictly defined code with an accuracy of better than 1 in 10,000 at most loca tions is arguably the most complex task performed by cells.

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Published November, 2010
By M.J. Tymms, Ismail Kola and Martin J. Tymms
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Availability: Available

As the major task of sequencing the human genome is near completion and full complement of human genes are catalogued, attention will be focused on the ultimate goal: to understand the normal biological functions of these genes, and how alterations lead to disease states.

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Published November, 2010
By M.J. Tymms and Martin J. Tymms
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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General initiation factors are involved in positioning RNA polymerase II on the core promoter, but the complex - teraction of these proteins and transcriptional activators binding to DNA e- ments outside the core promoter regulate the rate of transcriptional initiation.

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Published November, 2010
By Subhash C. Basu and Manju Basu
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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In vitro utilization of liposomes is now recognized as a powerful tool in many bioscience investigations and their associated clinical studies, e.g., liposomes in drug targeting;

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Published November, 2010
By Clare Wise
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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There have been significant advances in research involving the isolation and culture of epithelial cells in the past decade, and many new techniques have been developed.

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Published November, 2010
By Lorette C. Javois
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Availability: Available

Lorette Javois' timely new 2nd edition revises and updates her widely acclaimed collection of step-by-step immunocytochemical methods, one that is now used in many biological and biomedical research programs.

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Published November, 2010
By Marie-Isabel Aguilar
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Availability: Available

The introduction of high-performance liquid chromatography (HPLC) to the analysis of peptides and proteins some 25 years ago revolutionized the biological sciences by enabling the rapid and sensitive analysis of peptide and protein structure through the exquisite speed, sensitivity, and resolution that can be easily obtained.

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Published November, 2010
By Bryan John Smith
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Determination of the protein sequence is as important today as it was a half century ago, even though the techniques and purposes have changed over time. The first edition of Protein Sequencing Protocols was a "snapshot" of methods in use in protein biochemistry laboratories at the time, and this, the second edition, is likewise.

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Published November, 2010
By Janet J. Maguire and Anthony P. Davenport
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Availability: Available

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