Published December, 2020
By Vance Berger
Publisher: Taylor & Francis (CRC Press)
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Availability: Available

This book deals with randomization in clinical trials. Currently trials use permuted blocks randomization almost exclusively. Many researchers are aware of the drawbacks to this fatally flawed method, and while many are unaware of any better randomization methods, in fact several groups have proposed improvements, and also demonstrated the benef

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Published December, 2020
By Marc Buyse, Shigeyuki Matsui and Richard Simon
Publisher: Taylor & Francis (CRC Press)
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Availability: Available

This book offers statistical guidance on conducting clinical trials for predictive medicine. It covers statistical topics relevant to the main clinical research phases for developing molecular diagnostics and therapeutics. The book explains how to identify molecular biomarkers using DNA microarrays, validate the developed biomarkers, and confirm

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Published December, 2020
By Firas H. Kobeissy, Kevin K. W. Wang and Zhiqun Zhang
Publisher: Taylor & Francis (CRC Press)
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Availability: Available

This book explores the recent advances in the techniques and platforms used in biomarker research that have revolutionized the way we study, diagnose, and treat brain injury conditions. The contributors describe different biomarker studies pertaining to brain injury and other neurological disorders and analyze the different models and technologi

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Published December, 2020
By Sandeep M Menon, Kerry B. Barker, Siyan Xu, Ralph B. D'Agostino, Sr., Bo Jin, PhD, Sr. D'Agostino and PhD Jin
Publisher: Taylor & Francis (CRC Press)
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Availability: Available

Biosimilars have the potential to change the way we think about, identify, and manage health problems. They are already impacting both clinical research and patient care, and this impact will only grow as our understanding and technologies improve. Written by a team of experienced specialists in clinical development, this book discusses various

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Published December, 2020
By Monika Maya Wahi, Peter Seebach and Monika Wahi
Publisher: Taylor & Francis (CRC Press)
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Availability: Available

This book discusses how to do routine health data analysis, typically done in SAS, in R. It assumes that the audience has some experience in this area. Many SAS users want to try R, but R developers have not focused on health data analysis cookbooks. This book will allow them to add R to their analytic skills toolbox.

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Published December, 2020
By Wei Zhao and Harry Yang
Publisher: Taylor & Francis (CRC Press)
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Availability: Available

This comprehensive reference covers all aspects of drug combination research, from designing in vitro drug combination studies to analyzing clinical trial data. Featuring contributions from researchers in industry, academia, and regulatory agencies, this balanced text provides researchers with a solid understanding of the available statis

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Published December, 2020
By Ronald B. Geskus
Publisher: Taylor & Francis (CRC Press)
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Availability: Available

This practical and thorough book explains when and how to use models and techniques for the analysis of competing risks and intermediate states. It covers the most recent insights on estimation techniques and discusses in detail how to interpret the obtained results. Each chapter includes standard exercises; a software section on SAS, Stata, and

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Published December, 2020
By Jixian Wang
Publisher: Taylor & Francis (CRC Press)
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Availability: Available

This book explores a wide range of topics in exposure-response modeling, from traditional PKPD modeling to other areas in drug development and beyond. It incorporates numerous examples and software programs for implementing novel methods. The book emphasizes dose adjustment and treatment adaptation based on dynamic exposure-response models, illu

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Published December, 2020
By Ross L. Prentice and Shanshan Zhao
Publisher: Taylor & Francis (CRC Press)
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Availability: Available

Though much has been written on multivariate failure time data analysis methods, a unified approach to this topic has yet to be communicated. This book aims to fill that gap through a novel focus on marginal hazard rates and cross ratio modeling. Readers will find the content useful for instruction, for application in collaborative research and

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Published December, 2020
By Tamara Luti Rosenbaum Emir
Publisher: Taylor & Francis (CRC Press)
Rating:
Availability: Available

Neurobiology of TRP channels will review the current knowledge on how these important proteins participate in physiological and pathophysiological processes. The book is includes chapters by experts on the role of TRP channels in the peripheral and central nervous system.

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