Published December, 2020
By Marc Buyse, Tomasz Burzykowski, Geert Molenberghs, Ziv Shkedy, Wim Van der Elst, Theophile Bigirumurame, Leacky Muchene, Nolen Joy Perualila and Ariel Alonso
Publisher: Taylor & Francis (CRC Press)
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Availability: Available

When a true endpoint is difficult to use because of such factors as long follow-up times or prohibitive cost, it is sometimes possible to use a surrogate endpoint that can be measured in a more convenient or cost-effective way. This book focuses on the use of surrogate endpoint evaluation methods in practice, using SAS and R.

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Published December, 2020
By Ding-Geng (Din) Chen, Karl E. Peace and Pinggao Zhang
Publisher: Taylor & Francis (CRC Press)
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Availability: Available

This book will provide a thorough presentation of clinical trial methodology with detailed step-by-step illustrations on implementation in software R/SAS. The examples will be based on actual experience of the authors in many areas of clinical drug development. Actual examples of clinical trials will be presented and after understanding the appl

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Published December, 2020
By Eve Shapiro, Anthony M. DiGioia and Shapiro Eve
Publisher: Taylor & Francis (CRC Press)
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Availability: Available

The Patient Centered Value System is a three-part approach to co-designing improvements in healthcare delivery-collaborating with patients, families, and frontline providers to design the ideal state of care after listening to their wants and needs. Central to the Patient Centered Value System is seeing through the eyes of patients and families.

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Published December, 2020
By James Chou and Zhou Huaibei
Publisher: Taylor & Francis (CRC Press)
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Availability: Available

The 9th International Conference on Bioinformatics and Biomedical Engineering (iCBBE 2015) was held on September 18-20, 2015, Shanghai, China. This proceedings volume assembles papers from various professionals engaged in the fields of Biomedical Engineering, Bioinformatics and Computational Biology.

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Published December, 2020
By Bertrand Henri Rihn
Publisher: Taylor & Francis (CRC Press)
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This book explores nanoparticles, their chemical and physicals properties, and how they interact in biological systems with proteins, immune systems and targeted cells. Risk assessment of nanoparticles for human use is described, including: cellular paradigms, transcriptomics and toxicogenomics.

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Published December, 2020
By Toshiro Tango
Publisher: Taylor & Francis (CRC Press)
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Availability: Available

This book provides the application of generalized linear mixed-effects models and its related models in the statistical design and analysis of repeated measures adopted in randomized controlled trials. With increasing concerns about intra-patient variability of treatment effects, the traditional ANCOVA-type methods can no longer cope with these

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Published December, 2020
By Harry Yang
Publisher: Taylor & Francis (CRC Press)
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Availability: Available

The premise of Quality by Design (QbD) is that the quality of the pharmaceutical product should be based upon a thorough understanding of both the product and the manufacturing process. This state-of-the-art book provides a single source of information on emerging statistical approaches to QbD and risk-based pharmaceutical development. A compreh

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Published December, 2020
By Susan Halabi and Stefan Michiels
Publisher: Taylor & Francis (CRC Press)
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Availability: Available

This is a textbook on the design and analysis of cancer clinical trials. It opens with a discussion of the choice of endpoints before moving onto discuss various types of trials across all phases of study, including basket trials, non-inferiority trials and multi-arm trials.

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Published December, 2020
By Nathan William Tierney and William Tierney Nathan
Publisher: Taylor & Francis (CRC Press)
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Availability: Available

This book is designed in a format where any organization can read it and acquire the fundamentals and methodologies of Value Management. It is intended for healthcare delivery organizations in need of learning the specifics of achieving the implementation of value-based healthcare.

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Published December, 2020
By Thomas Ogg, Richard Leiper QC, Richard Leiper, Robert Merkin and Ewan McKendrick
Publisher: Taylor & Francis (CRC Press)
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Availability: Available

Since the financial crisis, one of the key priorities of the Financial Conduct Authority (FCA) and Prudential Regulation Authority (PRA) has been individual accountability. This book addresses the regulatory and employment law challenges that arise from the FCA's and PRA's requirements. The expert team of writers examine in depth

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