Main description:

Any professional concerned with immunology will be interested in this book dedicated to the memory of Milan Hasek, former director of the Prague Institute of Experimental Biology and Genetics. Prof. Hasek was a congenial scientist and most amiable person - a personal friend of almost all leading immunologists around the world. He was displaced from his post of director in 1970, yet had a lasting impact upon his students and the group known as the Prague School of Immunogenetics. The topics covered in the contributions range from tolerance, immune network, and immunogenetics to the immunology of bacterial and viral infections. They are written by 27 of Prof. Hasek's former co-workers who emigrated to western countries around or after 1968 and became well-known and distinguished scientists in the field. The papers include their personal reflections of the Prague Institute, their impressions upon arriving abroad and their interesting experimental work since then. The book also provides a complete bibliography of their publications after leaving Czechoslovakia.

Contents:

Milan Hasek: In Memoriam.- Once upon a time.- An imposing stature.- It took a few years.- My old friend.- Tolerance, Transplantation and Immune Network.- From Horses to Mice: Graft Rejection and Tolerance.- Tolerance and the Immune Network. T Cells Reactive to the Variable Domains of Immunoglobulins.- Milan Hasek, Lymphokines and Retroviruses.- Genetic Requirements for Interactions Between Cells for Murine Islet Allograft Rejection. Class I and Class II Antigens in Mouse Islet Rejection.- Chicken Major Histocompatibility Complex and Its Role in Disease.- Tolerance, the Thymus, and H-Y.- Autologous Mixed Lymphocyte Culture: Immunoregulatory Aspects.- Immunogenetics (MHC).- Mickey, Hugo, and Eve: A Study in the Evolution of the Major Histocompatibility Complex.- From Histocompatibility to Cancer.- HLA Antigens and Matching for Kidney Transplantation.- HLA Subtypes.- Zeroing in on the H-2 Complex.- Of Men and Mice.- Individual Differences Among Syngeneic Mice in Immune Response to Alloantigens and Modified Self-MHC-Antigens.- Immunology and Cytology in Bacterial, Viral and Tumor Diseases.- Immunological Analysis of Mycobacterial Disease.- Genetic Control of Susceptibility to Mycobacterial Infections.- From Serology of the Chicken MHC to Polymorphism of Malaria Antigen Genes.- Virus-Induced Neutropenia.- Tumor Immunotherapy.- Radiation-Enhanced Oncogene Expression.- Oncogenes: A Pathologist's View.- Natural Killer Cells: Odyssey from Laboratory Artifact to Clinical Reality.- Allergy to Drugs and Other Chemicals Diagnosed by the Presence of Specific Memory Cells in Human Blood.- Contribution of Cytogenetics to Cancer Research: Endometrial Adenocarcinoma.- Appendix A: Fondation De France.- Appendix B: Memoranda.- Name and Subject Index.