Main description:

Accumulating evidence supports the role of defects in post-transcriptional gene regulation in the development of cancer. "RNA and Cancer" focuses on the recent advances in our understanding of post-transcriptional gene regulation, especially RNA processing and its role in cancer development and treatment.

Contents:

Foreword.- Coupling between Transcription and Alternative Splicing.- Detection of Alternatively Spliced or Processed RNAs in Cancer using Oligonucleotide Microarray.- Cancer-associated Perturbations in Alternative Pre-messenger RNA Splicing.- Alternative Splicing of Tumor Suppressors and Oncogenes.- Imaging Alternative Splicing and Epithelial Plasticity in Tumor Cells and Tumors.- Alternative pre-mRNA splicing and regulation of cell death.- MIA melanoma?.- RNA localization/degradation.- RNA binding proteins and cancer.- Oligonucleotide cancer therapeutics.- Effects of anti-cancer drug on splicing.- Index.