Main description:

The skin is the largest human organ system. Loss of skin integrity due to injury or illness results in a substantial physiologic imbalance and ultimately in severe disability or death. From burn victims to surgical scars and plastic surgery, the therapies resulting from skin tissue engineering and regenerative medicine are important to a broad spectrum of patients.

Skin Tissue Engineering and Regenerative Medicine provides a translational link for biomedical researchers across fields to understand the inter-disciplinary approaches which expanded available therapies for patients and additional research collaboration. This work expands on the primary literature on the state of the art of cell therapies and biomaterials to review the most widely used surgical therapies for the specific clinical scenarios.

Contents:

Foreword
Introduction
1. Anatomy, Physiology, Histology, & Immunohistochemistry of Human Skin
2. Molecular & Cellular Biology of Wound Healing and Skin Regeneration
3. Tissue Processing and Staining for Histological Analyses
4. Clinical Management of Wound Healing and Hypertrophic Scarring
5. Process development & Manufacturing of Human and Animal Acellular Dermal Matrices
6. Clinical Applications of Acellular Dermal Matrices in Reconstructive Surgery
7. Advances in Acellular Extracellular Matrices (ECM) for Wound Healing
8. Natural Biomaterials for Skin Tissue Engineering
9. Synthetic Biomaterials for Skin Tissue Engineering
10. Hybrid Biomaterials for Skin Tissue Engineering
11. Biologic Skin Substitutes
12. Wound Healing: A Comprehensive Wound Assessment and Treatment Approach
13. Current Innovations for the Treatment of Chronic Wounds
14. The Surgical Management of Burn Wounds
15. Advances in Isolation and Expansion of Human Cells for Clinical Applications
16. Cutaneous Applications of Stem Cells for Skin Tissue Engineering
17. Advances in Biopharmaceutical Agents & Growth Factors for Wound healing & Scarring
18. Skin Models for Drug Development & Biopharmaceutical Industry
19. Animal Models for Wound Healing
20. Human Skin Bioprinting: Trajectory & Advances
21. Translational Research of Skin Substitutes & Wound Healing Products