Main description:

This concise, truncated version of Zini and Agarwal's Sperm Chromatin: Biological and Clinical Applications in Male Infertility and Assisted Reproduction offers select, clinical chapters for a handy, more affordable, state-of-the-art resource. Sperm Chromatin for the Clinician addresses such vital issues as: -Male subfertility and sperm chromatin damage -Aging and sperm DNA damage -Cancer and implications for sperm quality -Environmental factors -Cryopreservation and sperm DNA integrity -Postnatal effects of sperm chromatin damage Practical for clinicians and researchers alike, Sperm Chromatin for the Clinician contains all of the need-to-know information about this cutting-edge topic in reproductive medicine.

Contents:

Part I: Biological Determinants of Sperm Chromatin Damage.- Sperm Chromatin: An Overview.- Spermatogenesis: An Overview.- Role of Oxidative Stress in the Etiology of Sperm DNA Damage.- Abortive Apoptosis and Sperm Chromatic Damage.- Spermiogenesis in Sperm Genetic Integrity.- Part II: Clinical Aspects of Sperm Chromatin Damage.- Male Subfertility and Sperm Chromatin Damage.- Aging and Sperm DNA.- Cancer in Males: Implications for Sperm Quality, Fertility, and Progeny Outcome.- Sperm Chromatin and Environmental Factors.- Effects of Male Accessory Gland Infection on Sperm Parameters.- Antioxidants and Sperm DNA Damage.- Part III: Sperm Chromatin and Assisted Reproductive Technologies (ART).- The Impact of Sperm Processing and Cryopreservation on Sperm DNA Integrity.- Sperm Chromatin and ART (IUI, IVF and ICSI).- Sperm DNA Damage and Pregnancy Loss after IVF and ICSI.- Postnatal Effects of Sperm Chromatin Damage.- Evaluation of Chromatin and DNA Integrity in Testicular Sperm.- Clinical Utility of Sperm DNA Integrity Tests.