Main description:

The Choroid Plexus and Cerebrospinal Fluid: Emerging Roles in CNS Development, Maintenance, and Disease Progression combines new and established work to allow for cross-disciplinary discussion and showcase newfound excitement surrounding the choroid plexus and cerebrospinal fluid (CSF). This book is of great utility to neuroscientists interested in biological questions about cancer, multiple sclerosis, Alzheimer's, choroid plexus, or CSF research, and especially for researchers looking to expand their research into later stages of their disease of interest, such as metastasis. No other resource is currently available which addresses these issues in this fashion. The focus on the choroid plexus provides a practical resource on modeling clinical issues influenced by this brain region for researchers from students to principal investigators.

Contents:

1. Introduction to the Ventricular System and Choroid Plexus Tatsuhiro Fujii, Joshua Youssefzadeh, Michael Novel and Josh Neman

2. Development of brain ventricles and choroid plexus Ellen M. Carpenter

3. Choroid plexus: Structure and Function Florence M. Hofman and Thomas C. Chen

4. Towards an artificial choroid plexus, concept and clinical implications Thomas Brinker and John Morrison

5. Choroid Plexus Tumors Sean A. Grimm and Marc C. Chamberlain

6. Role of Blood Brain Barrier, Choroid Plexus, and Cerebral Spinal Fluid in Extravasation and Colonization of Brain Metastases Cecilia Choy and Josh Neman

7. The Role of the Choroid Plexus in the Pathogenesis of Multiple Sclerosis Vahan Martirosian, Alex Julian and Josh Neman

8. The Choroid Plexus and Cerebrospinal Fluid system: roles in neurodegenerative diseases Jerome Badaut and Jean-Francois Ghersi-Egea

9. Delivery Considerations for Targeting the Choroid Plexus-Cerebrospinal Fluid Route Thomas C. Chen

Glossary