Main description:

The book provides an overview on how the gut microbiome contributes to human health. The readers will get profound knowledge on the connection between intestinal microbiota and immune defense systems. The tools of choice to study the ecology of these highly-specialized microorganism communities such as high-throughput sequencing and metagenomic mining will be presented. In addition the most common diseases associated to the composition of the gut flora are discussed in detail. The book will address researchers, clinicians and advanced students working in biomedicine, microbiology and immunology.

Contents:

Chapter 1: Introduction (Haller)Chapter 2: Composition and function of the gut microbiome (Blaut; Postdam/+)Chapter 3: Clinical implementation of high-throughtput sequencing (Gessner, Regensburg/+) Chapter 4: Metagenomes (Florian Fricke, Hohenheim/+)Chapter 5: Gut microbial ecology of the human populations (John Baines, Kiel)Chapter 6: Microbiome and diet (Danilo Ercolino, Naples, Italy)Chapter 7-11: Microbiome and gut immunity- Innate (Jan Wehkamp, Julia Frick, Tubingen)- Epithelium (Christoph Becker/Claudia Gunther, Erlangen)- T cells (Jochen Huhn, Braunschweig/+) - B cells (Oliver Pabst, Aachen/+)- Early Life (Mathias Hornef, Aachen/+)Chapter 12-19: Microbiome and Disorders- Inflammatory Bowel Diseases (Haller/+)- Allergy (Biedermann, Munchen/+)- Graft-versus-Host Disease (Holler, Regensburg/+)- Infection (Barbel Stecher; Munchen/+)- Cancer (Sebastian Zeissig; Dresden/+)- Obesity (Thomas Clavel, Munchen/+)- Liver (Ina Bergheim, Wien/+)- Neurological disorders (Christoph Thoeringer, Munchen/+)Chapter 20: Fecal Transplantations and clinical application (Brita Siegmund, Berlin/+) Netherlands/+)Chapter 21: Gnotobiology (Andre Bleich, Hannover/+)