Contents:

Section 1-Pathogenic Aspects.- 1 Metabolic basis for disturbed keratinization in ichthyosis and other diseases.- 2 Essential fatty acids and skin scaliness.- 3 Epidermal lipogenesis in ichthyosis.- 4 Lipid synthesis in ichthyotic conditions.- 5 Immunofluorescence studies in ichthyosis vulgaris.- 6 Growth characteristics of the epidermis in the ichthyotic disorders.- 7 The proteins of epidermis in relation to normal and abnormal keratinization.- 8 The epidermis in Refsum's disease (heredopathia atactica polyneuritiformis).- 9 Ultrastructural features of ichthyotic skin in Refsum's syndrome.- 10 Ultrastructural criteria for the distinction of different types of inherited ichthyoses.- 11 Freeze-fracture preliminary observations in ichthyosis vulgaris.- 12 Morphological and quantitative assessment of physical changes in the horny layer in ichthyosis.- Section 2-Clinical and Genetic Aspects.- 13 Less common scaling dermatoses.- 14 Genetic heterogeneity in the ichthyoses.- 15 Inherited ichthyosiform dermatoses in infants and children.- 16 Follicular ichthyosiform disorder.- 17 Two cases of unusual ichthyosis.- Section 3-Treatment.- 18 The effect of urea on the skin with special reference to the treatment of ichthyosis.- 19 Pharmaceutical developments in the production of delivery systems for treating ichthyotic conditions.- 20 Efficacy of a skin cream containing pyrrolidone carboxylic acid in reducing the incidence of subclinical dry skin.- 21 Ichthyosiform erythroderma. 10 years treatment with retinoic acid.- 22 Aspects of long-term treatment of ichthyotic dermatoses with vitamin A acid.- 23 Treatment of disorders of keratinization with an oral stereoisomer of retinoic acid.