Main description:

We have witnessed a rapid development within the field of the kidney and hypertension in diabetes mellitus. A significant amount of work within the traditional areas has been published, and several new dimensions are now being developed, mostly in the experimental setting. These dimensions are discussed in several chapters of this new edition, The Kidney and Hypertension in Diabetes Mellitus, Fourth Edition.
This volume endeavors to cover all aspects of renal involvement in diabetes. It is written by colleagues who are themselves active in the many fields of medical research covered in this volume: epidemiology, physiology and pathophysiology, laboratory methodology and renal pathology.

Contents:

Some Keys to the Literature. Prefaces. 1. Historical Aspects of Diabetes and Diabetic Renal Disease; T. Deckert. 2. The Nature of the Diabetic Glomerulus: Pressure-Induced and Metabolic Aberrations; P. Cortes, B.L. Riser. 3. Definition of Diabetic Renal Disease in Insulin-Dependent Diabetes mellitus Based on Renal Function Tests; C.E. Mogensen. 4. Retinopathy in Relation to Albuminuria and Blood Pressure in IDDM; N. Chaturvedi, J.H. Fuller. 5. Microalbuminuria and Cardivascular Disease; S.M. Thomas, G. Viberti. 6. The Heart in Diabetes: Results of Trials; G. Zuanetti, et al. 7. Albuminuria in Non-Insulin-Dependent Diabetes - Renal or Extra Renal Disease? A. Schmitz. 8. The Clinical Course of Renal Disease in Caucasian NIDDM-Patiens; S. Nielsen, A. Schmitz. 9. Use of Albumin/Creatinine Ratio in Patient Care and Clinical Studies; J.H. Warram, A. Krolewzki. 10. Serum Creatinine and Other Measures of GFR in Diabetes; P. Rossing. 11. Familial Factors in Diabetic Nephropathy; D.J. Petitt, et al. 12. Genetics and Diabetic Nephropathy; M. Marre, B. Bouhanick. 13. The Concept of Low Birth Weight and Renal Disease; J.R. Nyengaard, E. Vestbo. 14. Effect of Insulin on the Kidney and the Cardiovascular System; E. Ferrannini. 15. Diabetes, Hypertension, and Kidney Disease in the PIMA Indians; W.C. Knowler, et al. 16. Value of Screening for Microalbuminuria in People with Diabetes as well as in the General Population; B. Feldt-Rasmussen, et al. 17. Incidence of Nephropathy in IDDM as Related toMortality. Cost and Benefits of Early Intervention; K. Borch-Johnsen. 18. Measurement of Albumin and Other Urinary Proteins in Low Concentration in Diabetes mellitus: Techniques and Clinical Significance; D.J.F. Rowe, W. Gatling. 19. Office Tests for Microalbuminuria; P.L. Poulsen. 20. Exercise and the Kidney in Diabetes; C.E. Mogensen. 21. Von Willebrand Factor, Dysfunction of the Vascular Endothelium, and the Development of Renal and Vascular Complications in Diabetes; C.D.A. Stehouwer. 22. Smoking and Diabetic Nephropathy; P.T. Sawicki. 23. Light Microscopy of Diabetic Glomerulopathy: the Classic Lesion; S. Olsen. 24. Renal Ultrastructural Changes in Microalbuminuric IDDM-Patients; H.-J. Bangstad, et al. 25. Renal Structure in Non Insulin-Dependent Diabetic Patients with Micro-albuminuria; P. Fioretto, et al. 26. Sodium-Hydrogen Antiport, Cell Function and Susceptibility to Diabetic Nephropathy; R. Trevisan, G. Viberti. 27. Advanced Glycation End-Products and Diabetic Renal Disease; M. Cooper, G. Jerums. 28. Protein Kinase C in Diabetic Renal Involvement, the Perspective of Inhibition; D. Koya, G.L. King. 29. Biochemical Aspects of Diabetic Nephropathy; E.D. Schleicher. 30. The Steno Hypothesis and Glomerular Basement Membrane Biochemistry in Diabetic Nephropathy; A. Kofoed-Enevoldsen. 31. Volume Homeostasis and Blood Pressure in Diabetic States; J.A. O'Hare, J.B. Ferriss. 32. Pathogenesis of Diabetic Glomerulopathy: The Role of Glomerular Hemodynamic Factors; S. Anderson. 33. The Role of Growth Hormone, Insulin