Main description:

The Makings of a Clinical Protocol: A Journey from Pure to Applied Biomedical Research and Beyond presents step-by-step details on how to develop a clinical protocol to both researchers and students involved in biomedical research. It discusses several protocols as case studies to illustrate the point that pure and applied research are interdependent upon, and mutually beneficial to each other. The cases examined cover diverse topics of biomedical field and can be easily adapted to fulfill readers' specific needs. This is a valuable resource for researchers, students and anyone interested in learning more about clinical protocol.

Contents:

1. Rooted tRNAomes and evolution of the genetic code
2. Aminoacyl-tRNA synthetase evolution and sectoring of the genetic code
3. Evolution of life on earth: Polymers ? Minihelices ? Cloverleaf tRNA, Type I and Type II tRNAs aaRS
4. Type II tRNAs and evolution of translation systems and the genetic code
5. An additional, complementary mechanism of action for folic acid in the treatment of megaloblastic anemia
6. Non-enzymatic methylation of cytosine in RNA by S-adenosylmethionine and implications for the evolution of translation
7. Evolution of life on Earth: tRNA, aminoacyl-tRNA synthetases and the genetic code
8. The 3 Minihelix tRNA Evolution Theorem
9. Methylating agents as adjunct therapy to chemotherapeutic alkylating medications for improved outcomes in chronic lymphocytic leukemia: A case study
10. Chaos, Order and Systematics in Evolution of the Genetic Code
11. Evolution of the genetic code