Main description:

The Molecular Immunology of Neurological Diseases provides a comprehensive review of current updates in molecular immunogenetics of different neurological diseases. Readers will learn about the role of immune cells and their modulation strategies to help in the development of therapeutic approaches for both acute and chronic neurodegenerative disorders. There is no other book available on the topic. It has long been thought that the brain is an immune-privilege organ with very limited immune response. However recent studies have made clear that both systemic 'brain' and peripheral 'blood' immune cell responses play key roles in determining brain pathology in neurodegenerative disorders.

This book summarizes the role of immune cell activation in the central nervous system microenvironment in acute and chronic neurodegenerative disorders. In addition, it discusses the key role of immune cells and their modulation strategies for the development of current therapeutic approaches.

Contents:

1. Molecular Basis of Neurological Disorders 2. Immunological Genes Expression in the Aged Brain 3. Immunogenetic Basis of Neurological Disorders 4. Immunological Protein Regulation in Neurodegenerative Disorders 5. Immunogenetics of Muscular Dystrophy 6. Host and Viral Genetic Factors Which Influence Viral Neurotropism 7. Neuro-Oncogenesis in the Development of Neuro-Ectodermal Cancers 8. Neurological Diseases and Mitochondrial Genes 9. Viral Genes in Neurological Disorders 10. A Gene Map of Brain Injury Disorders 11. Immunogenetics of Migraine 12. Immunogenetics of Neuropathy Disease