Main description:

Normative Biology, Husbandry, and Models, the third volume in the four volume set, The Mouse in Biomedical Research, encompasses 23 chapters whose contents provide a broad overview on the laboratory mouse's normative biology, husbandry, and its use as a model in biomedical research. This consists of chapters on behavior, physiology, reproductive physiology, anatomy, endocrinology, hematology, and clinical chemistry. Other chapters cover management, as well as nutrition, gnotobiotics and disease surveillance. There are also individual chapters describing the mouse as a model for the study of aging, eye research, neurodegenerative diseases, convulsive disorders, diabetes, and cardiovascular and skin diseases. Chapters on imaging techniques and the use of the mouse in assays of biological products are also included.

Contents:

1: Gross Anatomy 2: Mouse Physiology 3: Reproductive Biology of the Laboratory Mouse 4: Endocrinology: Bone as a Target Tissue for Hormonal Regulation 5: Hematology of the Laboratory Mouse 6: Clinical Chemistry of the Laboratory Mouse

Management, Techniques, and Husbandry 7: Gnotobiotics 8: Management and Design: Breeding Facilities 9: Design and Management of Research Facilities for Mice 10: Nutrition 11: Health Delivery and Quality Assurance Programs for Mice 12: Environmental and Equipment Monitoring 13: Biomethodology and Surgical Techniques 14: In-Vivo Whole-Body Imaging of the Laboratory Mouse

Use of Mice in Biomedical Research 15: Behavioral Testing 16: Cardiovascular Disease: Mouse Models of Atherosclerosis 17: Convulsive Disorders 18: Eye Research 19: Genetic Analysis of Rodent Obesity and Diabetes 20: Mouse Models in Aging Research 21: Mouse Models of Inherited Human Neurodegenerative Disease 22: Mouse Skin Ectodermal Organs 23: Quality Control Testing of Biologics