Main description:

This volume provides descriptions of the occurrence of the UPR, methods used to assess it, pharmacological tools and other methodological approaches to analyze its impact on cellular regulation. The authors explain how these methods are able to provide important biological insights.

Contents:

Section I: UPR and Cell Stress in Normal and Diseased Cells

The Unfolded Protein Response in Mouse Cerebral Cortex Nirinjini Naidoo
Immunohistochemical Detection of the Unfolded Protein Response in Atherosclerotic Plaques Sarka Lhotak and Richard C. Austin
The role of PDI as a survival factor in cardiomyocyte ischemia Stefano Toldo; Anna Severino; Antonio Abbate; Alfonso Baldi
Measurement of the Increase in Endoplasmic Reticulum Stress-Related Proteins and Genes in Adipose Tissue of Obese, Insulin-Resistant Individuals Guenther Boden and Salim Merali
Measurement of the unfolded protein response (UPR) in monocytes Tomas P. Carroll, Catherine M. Greene, and Noel G. McElvaney
Assessment of Endurance Exercise Training in Hepatic Endoplasmic Reticulum (ER) Stress Natalie Ann Chapados
Discovery approaches to UPR in athero - susceptible endothelium in vivo Mete Civelek, Elisabetta Manduchi, Gregory Grant, Christian J. Stoeckert Jr, Peter F. Davies
Assessment of endoplasmic reticulum stress and the unfolded protein response in endothelial cells Ines Witte & Sven Horke
Measuring the impact of cigarette smoke on the UPR Hong Zhao, Jin Yang, Lin Shan and Ellen D. Jorgensen
Induction and measurement of UPR and osmotic stress in the yeast Pichia pastoris Martin Dragosits, Diethard Mattanovich and Brigitte Gasser
Induction of ER stress response leading to programmed cell death in Trypanosoma brucei Hanoch Goldshmidt and Shulamit Michaeli
Measurement of Activation of the Endoplasmic Reticulum Stress Response in Autoimmune Myositis Heather M. Alger, Sree Rayavarapu and Kanneboyina Nagaraju
Activation of the unfolded protein response in human acute myeloid leukemia Julian A. Schardt , Beatrice U. Mueller and Thomas Pabst
Modulation of the Unfolded Protein Response by GRP78 in Prostate Cancer Gustaaf de Ridder, Rupa Ray, Uma K. Misra and Salvatore V. Pizzo
Endoplasmic Reticulum Stress In Brain Damage Ram Raghubir, Venkata Prasuja Nakka, and Suresh L. Mehta
Methods and Models for Monitoring UPR associated Macrophage Death during Advanced Atherosclerosis Edward B. Thorp
Detecting Autophagy in Response to ER Stress Signals in Cancer Guillermo Velasco, Maria Salazar, Sonia Hernandez-Tiedra, Sofia Torres, Mar Lorente, Manuel Guzman
The Unfolded Protein Response Induced By Salt Stress in Arabidopsis Miaoying Wang, Qiangyi Xu, and Ming Yuan
Measurement of ER Stress Response and Inflammation in the Mouse Model of Non-alcoholic Fatty Liver Disease Ze Zheng , Chunbin Zhang, Kezhong Zhang