Main description:

Discussing existing techniques, ongoing research, new approaches, and basic concepts in the treatment of nail diseases, Topical Nail Products and Ungual Drug Delivery summarizes the current knowledge and represents a jumping-off point for creating novel techniques of drug delivery across the nail.

A growing area of pharmaceutical research, the search for efficient delivery techniques that can cross the nail barrier has yielded several effective strategies, brought together in this book.

Topics Include

Nail anatomy, physiology, diseases, and treatment

Permeability of the nail plate

Topical nail formulations

Approaches to enhance ungual and trans-ungual drug delivery

In vitro and in vivo models to evaluate topical nail formulations

Nail sampling techniques

Bioengineering of the nail

Trans-ungual iontophoresis

Pharmacokinetics of drugs in the nail apparatus

Onychopharmacokinetics: proposed model insight

Photodynamic therapy of nail diseases

The nail as a surrogate for investigating drug use

Contents:

The Nail: Anatomy, Physiology, Diseases, and Treatment. Permeability of the Nail Plate. Topical Nail Formulations. Approaches to Enhance Ungual and Trans-Ungual Drug Delivery. In Vitro and In Vivo Models to Evaluate Topical Nail Formulations. Hydration-Controlled Nail System for the Evaluation of Topical Formulations and a Novel Nail Sampling Device. Bioengineering of the Nail: Transonychial Water Loss and Imaging Techniques, An Overview. Transungual Iontophoresis and Physical Drug Delivery Enhancement. Pharmacokinetics of Drugs in the Nail Apparatus. Onychopharmacokinetics: Proposed Model Insight. Photodynamic Therapy of Nail Diseases. Nail as a Surrogate for Investigating the Drug Use.