Main description:

This book presents both theoretical and practical aspects of transbronchial cryobiopsy, a new diagnostic technique for the detection of diffuse parenchymal lung disease that is attracting great interest in the scientific community. In the context of a multidisciplinary discussion, comprising radiologic-pathologic correlations, the authors examine the technical and safety issues - such as equipment, endoscopic setting, anesthesiologic approaches and bleeding control - on one hand, and the diagnostic yield and clinical meaning on the other.

The volume offers several case studies - including idiopathic pulmonary fibrosis, granulomatous disorders, interstitial pneumonias, rare lung disseminated tumors- that illustrate the high diagnostic yield and safety of this innovative technique. The book appeals to a wide readership, including residents, pulmonologists with expertise in diffuse parenchymal lung diseases, interventional pulmonologists, thoracic radiologists, pathologists, anesthesiologists, internists and rheumatologists.

Contents:

I Introduction to Diffuse Parenchimal Lung Disease.- 1 Diffuse Parenchymal Lung Disease: A Clinical Overview.- 2 Radiologic-pathologic Correlations in Diffuse Parenchymal Lung Disease.- 3 Multidisciplinary discussion in Diffuse Parenchymal Lung Disease.- II Transbronchial cryobiopsy.- 4 Cryobiopsy: Physics.- 5 Cryobiopsy: How it Happened.- 6 Technique and equipment in Transbronchial Cryobiopsy.- 7 Complications in Transbronchial Cryobiopsy.- 8 Immunohystochemistry and Molecular Biology in Transbronchial Cryobiopsy.- III Clinical role of Transbronchial Cryobiopsy.- 9 The Diagnostic Yield of Transbronchial Cryobiopsy.- 10 Clinical Meaning of Transbronchial Cryobiopsy.- 11 Pathologic considerations in Transbronchial Cryobiopsy.- 12 Future perspectives for Transbronchial Cryobiopsy in Diffuse Parenchymal Lung Disease.- IV Case series.- 13 Idiopahic Pulmonary Fibrosis.- 14 Chronic hypersensitivity pneumonitis.- 15 Other granulomatoses.- 16 Nonspecific interstitial pneumonia.- 17 Collagen vascular diseases.- 18 Smoking related ILDs.- 19 Lymphangioleiomyomatosis.- 20 Pleuroparenchymal fibroelastosis.- 21 Acute lung injury.- 22 Neoplasms.- 23 Rarities.