Main description:

As stated by The Cochrane Collaboration on their website, the practice of evidence-based medicine means integrating individual clinical expertise with the best available external clinical evidence from systematic research. Understanding Periodontal Research fills a significant gap in the literature by providing oral health and periodontal researchers with a comprehensive overview of the methodological aspects that are important when planning, conducting, and analyzing their research projects. It is designed to be easy to understand for beginners in the field, yet will also serve as a useful tool for those who are more experienced. Undergraduate and postgraduate dental students, dental hygienists, dental practitioners, and associated professionals who are interested in understanding the principles of periodontal research will all benefit from the clear information and guidance contained in this book.

Contents:

Evidence-based periodontology.- Ethical Considerations in Periodontal Research.- Overview of Clinical Research Design Architecture.- The Randomized Clinical Trials Design.- Biases in periodontal research.- Measurement reliability in periodontal research.- Compliance considerations in clinical trial design.- Performing systematic reviews and meta-analyses.- Statistical versus clinical significance in periodontal research.- Clinical practice guidelines in periodontology.- Multilevel analysis: site-tooth-patient level.- Contemporary Concepts in the Diagnosis of Periodontal Disease.- A guide to diagnostic accuracy studies in periodontology.- Clinical trials principles for evaluation of antimicrobial drugs in periodontal disease treatment.- The Hawthorne effect.- Clinical trials principles for evaluation of antimalodour products.- Specific issues in clinical trials on the evaluation of genetic factors in the pathology of periodontal disease.- Indices currently used in periodontal research.- Specific issues in epidemiological studies of periodontal disease.- Assessing confounding and effect modification in research involving periodontal disease and systemic diseases.- Animal models in periodontal research.