Published October, 2014
By Mouldy Sioud
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Availability: Available

RNA Interference: Challenges and Therapeutic Opportunities provides readers with recent advances in siRNA design, delivery, targeting and methods to minimize siRNA's unwanted effects.

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Published October, 2014
By Adam R. Karpf
Publisher: Springer (Springer-Verlag New York Inc.)
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Availability: Available

The purpose of this book is to provide an up to date review of the nature and consequences of epigenetic changes in cancer. These changes include alterations in global and promoter specific DNA methylation, activating and repressive histone modifications, and changes in higher order chromatin structures.

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Published October, 2014
By Lee-Jun C. Wong
Publisher: Springer (Springer-Verlag New York Inc.)
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Availability: Available

Mitochondrial cytopathies are mutations in the inherited maternal mitochondrial genome, or the nuclear DNA-mutation.

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Published October, 2014
By Peter B. Gahan
Publisher: Springer
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Availability: Available

DNA and RNA fractions have been isolated from the whole blood, serum, plasma, the surface of blood cells, urine, saliva and spinal fluid from both healthy individuals and clinical patients.

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Published October, 2014
By Mark Slevin
Publisher: Springer
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Angiogenesis is the growth of new blood vessels and is a key process which occurs during pathological disease progression.

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Published October, 2014
By William C.S. Cho and William C S Cho
Publisher: Springer
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Availability: Available

This timely publication includes chapters by world-renowned experts and focuses on our current understanding of miRNAs. It assesses their potential applications in cancer diagnosis, prognosis and therapeutic targets, and identifies areas for further research.

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Published October, 2014
By Richard Tutton
Publisher: Taylor & Francis (Routledge)
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A rigorous, critical examination of the promises of genomics to transform the economics and delivery of medicine, Genomics and the Reimagining of Personalized Medicine examines the consequences of the shift towards personalization for the way we think about and act on health and disease in society. As such.

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Published October, 2014
By Vipin Chandra Kalia
Publisher: Springer (Springer, India, Private Ltd)
Rating: 0.00
Availability: Available

Although QSIs do not affect growth and are less likely to impose selective pressure on bacteria, however, a few reports have raised doubts on the fate of QSIs.

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Published October, 2014
By Adam J. Dupuy and David A. Largaespada
Publisher: Springer (Springer-Verlag New York Inc.)
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Availability: Available

The goal of this work is summarize the contribution that insertional mutagenesis has made to our understanding of cancer. In addition, the impact of insertional mutagenesis in several gene therapy trials is discussed along with strategies to avoid such complications in future clinical trials.

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Published October, 2014
By Steve Horvath
Publisher: Springer (Springer-Verlag New York Inc.)
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Availability: Available

High-throughput measurements of gene expression and genetic marker data facilitate systems biologic and systems genetic data analysis strategies. Gene co-expression networks have been used to study a variety of biological systems, bridging the gap from individual genes to biologically or clinically important emergent phenotypes.

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