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MORE ABOUT THIS BOOK
Main description:
This two-volume work covers the molecular and cell biology, genetics and evolution of influenza viruses, the pathogenesis of infection, resultant host innate and adaptive immune response, prevention of infection through vaccination and approaches to the therapeutic control of infection.. Experts at the forefront of these areas provide critical assessments with regard to influenza virology, immunology, cell and molecular biology, and pathogenesis. Volume I provides overviews of the latest findings on molecular determinants of viral pathogenicity, virus entry and cell tropism, pandemic risk assessment, transmission and pathogenesis in animal species, viral evolution, ecology and antigenic variation, while Volume II focuses on the role of innate and adaptive immunity in pathogenesis, development of vaccines and antivirals.
Contents:
Part I: Molecular determinants of pathogenicity
The Hemagglutinin - a Determinant of Pathogenicity
Eva Boettcher-Friebertshauser, Wolfgang Garten, Mikhail Matrosovich, and Hans Dieter Klenk
Molecular determinants of pathogenicity in the polymerase complex
Gulsah Gabriel and Ervin Fodor
Part II: Virus entry and cell tropism
Receptor binding properties of the influenza virus hemagglutinin as a determinant of host range
Xiaoli Xiong, John W. McCauley, David A. Steinhauer
Acid-induced membrane fusion by the hemagglutinin protein and its role in influenza virus biology
Charles J. Russell
Part III: Transmission and Pandemics
Pandemic Preparedness and the Influenza Risk Assessment Tool (IRAT)
Nancy J. Cox, Susan C. Trock and Stephen A. Burke
Avian influenza virus transmission to mammals
S. Herfst, M. Imai, Y. Kawaoka and R.A.M. Fouchier
Transmission in the Guinea Pig Model
Anice C. Lowen, Nicole M. Bouvier and John Steel
Enhancement of influenza virus transmission by gene reassortment
Chengjun Li and Hualan Chen
Swine and Influenza: A Challenge to One Health Research
Robert E. Kahn, Wenjun Ma and Jurgen A. Richt
Part IV: Animal models and pathogenesis
Influenza Pathobiology and Pathogenesis in Avian Species
Monique S. Fran a and Justin D. Brown
Molecular determinants of influenza virus pathogenesis in mice
Ram P. Kamal, Jaqueline M. Katz, and Ian A. York
Mammalian models for the study of H7 virus pathogenesis and transmission
Jessica A. Belser and Terrence M. Tumpey
Pathogenesis and vaccination of influenza A virus in swine
Daniela S. Rajao, Tavis K. Anderson, Phillip C. Gauger, Amy L. Vincent
Secondary Bacterial Infections in Influenza Virus Infection Pathogenesis
Amber M. Smith and Jonathan A. McCullers
Part V: Evolution, Antigenic Variation
Evolution and Ecology of Influenza A viruses
Sun-Woo Yoon, Richard J. Webby and Robert G. Webster
Influenza A virus reassortment
John Steel and Anice C. Lowen
Antigenic Analyses of Highly Pathogenic Avian Influenza A Viruses
Ruben O Donis
PRODUCT DETAILS
Publisher: Springer (Springer International Publishing AG)
Publication date: October, 2014
Pages: 400
Weight: 7981g
Availability: Available
Subcategories: Immunology, Infectious Diseases, Microbiology, Public Health
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